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Displaying drugs 13426 - 13450 of 14021 in total
Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)).
Investigational
Matched Description: … Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib ... in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)). …
BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).
Investigational
Matched Iupac: … N-[(1R,2S,5R)-5-(tert-butylamino)-2-[(3S)-3-({7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl}amino)-2
Matched Description: … BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine ... and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC …
Bentracimab is under investigation in clinical trial NCT04286438 (Bentracimab (PB2452) in Ticagrelor-treated Patients With Uncontrolled Major or Life-threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure).
Investigational
Matched Description: … Bentracimab is under investigation in clinical trial NCT04286438 (Bentracimab (PB2452) in Ticagrelor-treated …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
IMCY-0141 is a synthetic peptide based on MOG (Myelin Oligodendrocyte Glycoprotein), a dominant autoantigen, designed to stop the progression of multiple sclerosis (MS) and the destruction of the myelin sheath protecting the nerves.
Investigational
Matched Description: … multiple sclerosis (MS) and the destruction of the myelin sheath protecting the nerves. ... MOG (Myelin Oligodendrocyte Glycoprotein), a dominant autoantigen, designed to stop the progression of
Cefilavancin is a covalently-linked glycopeptide-cephalosporin (beta-lactam) heterodimer antibiotic that exhibits substantially greater activity than its component parts against Gram-positive bacteria.
Investigational
Matched Iupac: … {[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-[(3-{[(1S,2R,18R,19R,22S,25R,28R,40S)-48- ... )oxan-2-yl]oxy}-22-(carbamoylmethyl)-5,47-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino ... carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium ... )pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^{3,6}.2^{ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
RPI-78M is being developed for the treatment of multiple sclerosis (MS). Other neurological disorders that may be served by RPI-78M include myasthenia gravis (MG), muscular dystrophy (MD) and amyotrophic lateral sclerosis (ALS).
Investigational
Matched Description: … RPI-78M is being developed for the treatment of multiple sclerosis (MS). …
IPH 1101 is a chemically-synthesized structural analog of non-conventional bacterial phosphoantigens which specifically activate the Vγ9Vδ2 T cell subset. IPH 1101 is the most advanced drug candidate of the γδ T cell platform
Investigational
Matched Description: … IPH 1101 is the most advanced drug candidate of the γδ T cell platform ... IPH 1101 is a chemically-synthesized structural analog of non-conventional bacterial phosphoantigens …
SJ-733 has been used in trials studying Malaria.
Investigational
Matched Iupac: … (3S,4S)-N-(3-cyano-4-fluorophenyl)-1-oxo-3-(pyridin-3-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinoline …
Matched Description: … SJ-733 has been used in trials studying Malaria. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sulprostone has been used in trials studying Abortion, Induced.
Investigational
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl]-N-methanesulfonylhept …
Matched Description: … Sulprostone has been used in trials studying Abortion, Induced. …
Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Description: … Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. ... Endostar has been investigated for the treatment of Non-small Cell Lung Cancer. …
3-allyfentanyl is a fentanyl derivative opioid that can cause itching, nausea and serious respiratory depression. Fentanyl and its analogs have killed thousands of people around the world as drugs of abuse.
Illicit
Matched Iupac: … N-phenyl-N-[(3S,4R)-1-(2-phenylethyl)-3-(prop-2-en-1-yl)piperidin-4-yl]propanamide …
Matched Description: … Fentanyl and its analogs have killed thousands of people around the world as drugs of abuse. …
Debamestrocel consists of autologous mesenchymal stromal cells secreting neurotrophic factors. Debamestrocel is under clinical development by BrainStorm Cell Therapeutics and is being investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).
Investigational
Matched Description: … Debamestrocel consists of autologous mesenchymal stromal cells secreting neurotrophic factors. ... under clinical development by BrainStorm Cell Therapeutics and is being investigated for the treatment of
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Description: … Betameprodine is a structural analogue of meperidine. ... an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
The α-anomer of D-galacturonic acid.
Experimental
Matched Iupac: … (2S,3R,4S,5R,6S)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid …
Matched Description: … The α-anomer of D-galacturonic acid. …
FavId, is an active immunotherapy that is based upon unique genetic information extracted from a patient's tumor.
Investigational
TC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder). TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than Inversine.
Investigational
Matched Description: … in a lower dose than Inversine. ... TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but …
The use of ferrous acetate over ferrous sulfate is currently undergoing an investigation by a clinical trial . It is also used for dying of fabric or leather and as a wood preservative.
Experimental
Matched Iupac: … lambda2-iron(2+) ion (2S)-2-aminobutanedioate …
Matched Description: … It is also used for dying of fabric or leather and as a wood preservative. ... The use of ferrous acetate over ferrous sulfate is currently undergoing an investigation by a clinical …
Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.
Experimental
Matched Iupac: … 4-(2-amino-1-hydroxyethyl)phenol …
Matched Description: … Anti-doping Agency (WADA) as of 2014. ... It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World …
Dasotraline is a serotonin, norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of Binge Eating Disorder, Adult Attention Hyperactivity Disorder, Attention Deficit Hyperactivity Disorder, and Adult Attention Deficit Hyperactivity Disorder.
Investigational
Matched Description: … norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of
Matched Salts cas: … 675126-08-6
Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells. Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.
Investigational
Matched Description: … Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells ... Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as …
Navarixin has been investigated for the treatment of Asthma.
Investigational
Matched Iupac: … 2-hydroxy-N,N-dimethyl-3-[(2-{[(1R)-1-(5-methylfuran-2-yl)butyl]amino}-3,4-dioxocyclobut-1-en-1-yl)amino …
Matched Description: … Navarixin has been investigated for the treatment of Asthma. …
Matched Salts cas: … 862464-58-2
Vestipitant has been investigated for the treatment of Tinnitus.
Investigational
Matched Iupac: … (2S)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperazine- …
Matched Description: … Vestipitant has been investigated for the treatment of Tinnitus. …
An antiferromagnetic material; constitutes the core of natural ferritin.
Experimental
Matched Description: … An antiferromagnetic material; constitutes the core of natural ferritin. …
Clinofibrate is a fibrate drug sold and marketed in Japan.
Experimental
Matched Iupac: … 2-(4-{1-[4-(1-carboxy-1-methylpropoxy)phenyl]cyclohexyl}phenoxy)-2-methylbutanoic acid …
Matched Description: … Clinofibrate is a fibrate drug sold and marketed in Japan. …
A natural product found in Cannabis sativa and Helichrysum species.
Experimental
Matched Iupac: … 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5-pentylbenzene-1,3-diol …
Matched Description: … A natural product found in Cannabis sativa and Helichrysum species. …
Displaying drugs 13426 - 13450 of 14021 in total