Displaying drugs 14101 - 14125 of 14815 in total
SIG-207
SIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified alginate spheres
Investigational
Matched Description: … SIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral ... vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified …
Valopicitabine
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Iupac: … (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus ... This blocks viral production of HCV RNA and thus viral replication. [from NCI] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus ... This blocks viral production of HCV RNA and thus viral replication. [from NCI] …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Setrusumab
Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density).
Investigational
Matched Description: … Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density). ... Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing …
Dubermatinib
Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
Investigational
Matched Iupac: … -1-sulfonamide ... 2-{[5-chloro-2-({4-[(4-methylpiperazin-1-yl)methyl]phenyl}amino)pyrimidin-4-yl]amino}-N,N-dimethylbenzene …
Matched Description: … Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor ... of AXL Kinase) in Patients With Previously Treated CLL). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor ... of AXL Kinase) in Patients With Previously Treated CLL). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Milciclib Maleate
Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy).
Investigational
Matched Iupac: … N,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1H,4H,5H-pyrazolo[4,3-h]quinazoline-3 …
Matched Description: … Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in ... Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in ... Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pegcantratinib
Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene).
Investigational
Matched Description: … of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene). ... Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy …
Hexadecyl Octanoate
Experimental
Enadenotucirev
Enadenotucirev is under investigation in clinical trial NCT02636036 (Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors).
Investigational
Matched Description: … and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors). ... Enadenotucirev is under investigation in clinical trial NCT02636036 (Phase I Study of Enadenotucirev …
VK-2809
VK-2809 is under investigation in clinical trial NCT02927184 (Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease).
Investigational
Matched Description: … VK-2809 is under investigation in clinical trial NCT02927184 (Safety and Tolerability of VK2809 in Patients …
Flotetuzumab
Flotetuzumab is under investigation in clinical trial NCT02152956 (Safety Study of MGD006 in Relapsed/Refractory Acute Myeloid Leukemia (AML) or Intermediate-2/High Risk MDS).
Investigational
Matched Description: … Flotetuzumab is under investigation in clinical trial NCT02152956 (Safety Study of MGD006 in Relapsed …
MK-6325
MK-6325 is under investigation in clinical trial NCT01329913 (Safety, Pharmacokinetics, and Pharmacodynamics of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003)).
Investigational
Matched Iupac: … (3R,20R,24R,28S,34E,36S,38R,41S)-9-methoxy-N-[(1-methylcyclopropyl)sulfonyl]-26,40,42-trioxo-4,25-dioxa …
Matched Description: … of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003)). ... MK-6325 is under investigation in clinical trial NCT01329913 (Safety, Pharmacokinetics, and Pharmacodynamics …
Matched Description: … of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003)). ... MK-6325 is under investigation in clinical trial NCT01329913 (Safety, Pharmacokinetics, and Pharmacodynamics …
Lunsekimig
Lunsekimig is under investigation in clinical trial NCT06102005 (Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma).
Investigational
Matched Description: … Lunsekimig is under investigation in clinical trial NCT06102005 (Dose Ranging Study of Lunsekimig Compared ... With Placebo-control in Adult Participants With Moderate-to-severe Asthma). …
Selitrectinib
Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers).
Investigational
Matched Iupac: … )-9-fluoro-15-methyl-2,11,16,20,21,24-hexaazapentacyclo[16.5.2.0^{2,6}.0^{7,12}.0^{21,25}]pentacosa-1( …
Matched Description: … Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients …
Matched Description: … Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients …
Dalantercept
Dalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma).
Investigational
Matched Description: … Dalantercept is under investigation in clinical trial NCT00996957 (Study of ACE-041 in Patients With …
EPI-589
EPI-589 is under investigation in clinical trial NCT02460679 (Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)).
Investigational
Matched Iupac: … (2R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide …
Matched Description: … EPI-589 is under investigation in clinical trial NCT02460679 (Safety and Biomarker Study of EPI-589 in …
Matched Description: … EPI-589 is under investigation in clinical trial NCT02460679 (Safety and Biomarker Study of EPI-589 in …
Rinucumab
Rinucumab is under investigation in clinical trial NCT02418754 (Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-related Macular Degeneration (AMD)).
Investigational
Matched Description: … Rinucumab is under investigation in clinical trial NCT02418754 (Study of Intravitreal REGN2176-3 in Participants …
Selgantolimod
Selgantolimod is under investigation in clinical trial NCT03491553 (Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-suppressed Adults With Chronic Hepatitis B).
Investigational
Matched Iupac: … (2S)-2-({2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl}amino)-2-methylhexan-1-ol …
Matched Description: … Activity of Selgantolimod in Virally-suppressed Adults With Chronic Hepatitis B). ... Selgantolimod is under investigation in clinical trial NCT03491553 (Safety, Tolerability and Antiviral …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Activity of Selgantolimod in Virally-suppressed Adults With Chronic Hepatitis B). ... Selgantolimod is under investigation in clinical trial NCT03491553 (Safety, Tolerability and Antiviral …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Taniborbactam
Taniborbactam is under investigation in clinical trial NCT03840148 (Safety and Efficacy Study of Cefepime/vnrx-5133 in Patients With Complicated Urinary Tract Infections).
Investigational
Matched Description: … Taniborbactam is under investigation in clinical trial NCT03840148 (Safety and Efficacy Study of Cefepime ... /vnrx-5133 in Patients With Complicated Urinary Tract Infections). …
Pirlimycin
Pirlimycin hydrochloride is an antibiotic belonging to the lincosamide class. Often marketed as Pirsue, this drug is used to treat mastitis in cattle.
Vet approved
Matched Iupac: … (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]- …
Matched Description: … Often marketed as _Pirsue_, this drug is used to treat mastitis in cattle. ... Pirlimycin hydrochloride is an antibiotic belonging to the _lincosamide_ class. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Often marketed as _Pirsue_, this drug is used to treat mastitis in cattle. ... Pirlimycin hydrochloride is an antibiotic belonging to the _lincosamide_ class. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Moschus berezovskii musk sac resin
Moschus berezovskii musk sac resin is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Moschus berezovskii musk sac resin is an animal extract used in some OTC (over-the-counter) products. …
Fluasterone
Has antiproliferative effects on HIV-1 and reduces HIV-1 replication.
Investigational
Matched Description: … Has antiproliferative effects on HIV-1 and reduces HIV-1 replication. …
Displaying drugs 14101 - 14125 of 14815 in total