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Mevastatin or compactin is a cholesterol-lowering agent isolated from Penicillium citinium. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that...

Experimental

Matched Description: … The compound was proposed to bind to the reductase enzyme and was named compactin. …

ERB-196

Experimental

Displaying drugs 14251 - 14275 of 15036 in total

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3,4-Dihydro-2h-Pyrrolium-5-Carboxylate

Sri-9662

7-cyano-7-deazaguanine

4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid

4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole

ANILINOMETHYL GLUCO-PHENYLIMIDAZOLE

N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline

(2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE

(2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE

2-Methyl-2-propanyl [(1R)-2-methyl-1-(1,3,4-oxadiazol-2-yl)propyl]carbamate

2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM

Mepixanox

Molidustat

3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine

Gluco-Phenylimidazole

4-Carboxyphenylboronic Acid

6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine

5-(2-METHOXYPHENYL)-2-FUROIC ACID

(2,6-Dimethylphenoxy)acetic acid

3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE

N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine

4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid

(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid

Mevastatin

ERB-196