Displaying drugs 126 - 150 of 6215 in total
Baloxavir marboxil
Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of baloxavir with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl...
Approved
Investigational
Matched Iupac: … {[(3R)-2-[(2S)-12,13-difluoro-9-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl]-9,12 ... -dioxo-5-oxa-1,2,8-triazatricyclo[8.4.0.0^{3,8}]tetradeca-10,13-dien-11-yl]oxy}methyl methyl carbonate …
Matched Description: … virus proliferation. ... More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza ... by the US approval in October, 2018. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Products: … XOFLUZA 40 MG FİLM KAPLI TABLET, 1 ADET ... XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET ... XOFLUZA 40 MG FİLM KAPLI TABLET, 2 ADET …
Matched Description: … virus proliferation. ... More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza ... by the US approval in October, 2018. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Products: … XOFLUZA 40 MG FİLM KAPLI TABLET, 1 ADET ... XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET ... XOFLUZA 40 MG FİLM KAPLI TABLET, 2 ADET …
Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 15B individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae ... * serotype 15B individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Matched Description: … Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae ... * serotype 15B individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … a vaccine. ... Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Categories: … Inactivated Meningococcal Vaccine …
Matched Description: … a vaccine. ... Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Categories: … Inactivated Meningococcal Vaccine …
Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae ... * serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Matched Description: … Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae ... * serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 12F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae ... * serotype 12F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Matched Description: … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae ... * serotype 12F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin …
Matched Categories: … Inactivated Pneumococcal Vaccine …
Oseltamivir
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Synonyms: … Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate ... 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha …
Matched Iupac: … ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate …
Matched Description: … viruses A (including pandemic H1N1) and B. ... antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus ... children younger than 2 years, people over 65 years, people with some chronic conditions or immunosuppression …
Matched Salts cas: … 204255-11-8 …
Matched Iupac: … ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate …
Matched Description: … viruses A (including pandemic H1N1) and B. ... antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus ... children younger than 2 years, people over 65 years, people with some chronic conditions or immunosuppression …
Matched Salts cas: … 204255-11-8 …
Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen
Approved
Investigational
Matched Name: … Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen …
Cyproheptadine
Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
Approved
Matched Synonyms: … 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine ... 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine ... 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine …
Matched Iupac: … 1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}piperidine …
Matched Description: … Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … CYPRO - B SYRUP ... ไซโปร 2 ... แอพพีดีน 2 มก. …
Matched Iupac: … 1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}piperidine …
Matched Description: … Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … CYPRO - B SYRUP ... ไซโปร 2 ... แอพพีดีน 2 มก. …
LetibotulinumtoxinA
The aesthetic utility of botulinum toxin was discovered incidentally following its initial use in the treatment of facial spasmodic disorders in the early 1970s. The first aesthetic use of botulinum toxin was reported in 1989, when onabotulinumtoxinA (Botox) was used as a treatment for facial asymmetry resulting from iatrogenic facial...
Approved
Matched Synonyms: … BoNT/A-DS …
Matched Description: … [L42330] It is a 900 kDa multimeric complex comprising a 150 kDa toxin, a 130 kDa non-toxic non-haemagglutinating ... [L42330] LetibotulinumtoxinA has been a market-leading cosmetic product in South Korea for a number of ... [A249920] LetibotulinumtoxinA is a type A botulinum neurotoxin produced from fermentation of _Clostridium …
Matched Categories: … Botulinum Toxins, Type A …
Matched Description: … [L42330] It is a 900 kDa multimeric complex comprising a 150 kDa toxin, a 130 kDa non-toxic non-haemagglutinating ... [L42330] LetibotulinumtoxinA has been a market-leading cosmetic product in South Korea for a number of ... [A249920] LetibotulinumtoxinA is a type A botulinum neurotoxin produced from fermentation of _Clostridium …
Matched Categories: … Botulinum Toxins, Type A …
Amitriptyline
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Synonyms: … 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine ... 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine ... 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Δ5,γ-propylamine …
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ... ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961 …
Matched Salts cas: … 17086-03-2 …
Matched Mixtures name: … Etrafon A Tab ... Apo Peram Tab 3-15 ... PMS-levazine 3/15 Tab …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ... ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961 …
Matched Salts cas: … 17086-03-2 …
Matched Mixtures name: … Etrafon A Tab ... Apo Peram Tab 3-15 ... PMS-levazine 3/15 Tab …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Gallium Ga-68 gozetotide
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Synonyms: … 68Ga-Psma-11 ... Ga-68 PSMA-11 ... PSMA-11 Ga 68 …
Matched Iupac: … (68Ga)gallium(3+) 3-(3-{[(2-{[(5-{2-[(5-{[(5S)-5-carboxy-5-({[(1S)-1,3-dicarboxypropyl]carbamoyl}amino ... )pentyl]carbamoyl}pentyl)carbamoyl]ethyl}-2-hydroxyphenyl)methyl](carboxylatomethyl)amino}ethyl)(carboxylatomethyl …
Matched Description: … Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical ... [L27006] On December 1, 2020, Ga-68 PSMA-11 was approved by the FDA as the first molecular-targeted ... membrane antigen (PSMA). …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Gallium Ga-68 PSMA-11 …
Matched Iupac: … (68Ga)gallium(3+) 3-(3-{[(2-{[(5-{2-[(5-{[(5S)-5-carboxy-5-({[(1S)-1,3-dicarboxypropyl]carbamoyl}amino ... )pentyl]carbamoyl}pentyl)carbamoyl]ethyl}-2-hydroxyphenyl)methyl](carboxylatomethyl)amino}ethyl)(carboxylatomethyl …
Matched Description: … Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical ... [L27006] On December 1, 2020, Ga-68 PSMA-11 was approved by the FDA as the first molecular-targeted ... membrane antigen (PSMA). …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Gallium Ga-68 PSMA-11 …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying …
Matched Description: … expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). ... Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that ... [L43282] The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes …
Matched Description: … expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). ... Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that ... [L43282] The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes …
Elranatamab
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … B-CELL MATURATION ANTIGEN (BCMA) CLUSTER OF DIFFERENTIATION 3 (CD3) BISPECIFIC MONOCLONAL ANTIBODY (MAB ... -CHAIN, (223->217')(2 ... -CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06863059 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS …
Matched Description: … Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. ... It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs …
Matched Categories: … Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Matched Description: … Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. ... It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs …
Matched Categories: … Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Zaleplon
Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Synonyms: … 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Description: … It is known as a nonbenzodiazepine hypnotic. ... Zaleplon is a sedative/hypnotic, mainly used for insomnia. ... Zaleplon is a schedule IV drug in the United States. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... GABA-A Receptor Agonists ... gamma-Aminobutyric Acid A Receptor Agonist …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Description: … It is known as a nonbenzodiazepine hypnotic. ... Zaleplon is a sedative/hypnotic, mainly used for insomnia. ... Zaleplon is a schedule IV drug in the United States. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... GABA-A Receptor Agonists ... gamma-Aminobutyric Acid A Receptor Agonist …
rsPSMA Vaccine
Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA (Schulke et al., PNAS 100:12590, 2003)....
Approved
Investigational
Matched Synonyms: … Recombinant soluble prostate-specific membrane antigen (rsPSMA) vaccine …
Matched Description: … Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly ... subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA ... preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a …
Matched Description: … Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly ... subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA ... preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a …
Azatadine
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaene …
Matched Mixtures name: … XL-3 VR ... XL-3 XTRA …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaene …
Matched Mixtures name: … XL-3 VR ... XL-3 XTRA …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle
Approved
Matched Name: … Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle …
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ ... BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET İĞNESİZ …
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ ... BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET İĞNESİZ …
Pepsin
Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products .
Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Synonyms: … Pepsin A …
Matched Description: … a hormonally mediated process. ... Interestingly, it has been used as a marker for laryngopharyngeal reflux (LPR), which is a common illness ... Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, …
Matched Mixtures name: … Debiline H …
Matched Categories: … Pepsin A, antagonists & inhibitors …
Matched Description: … a hormonally mediated process. ... Interestingly, it has been used as a marker for laryngopharyngeal reflux (LPR), which is a common illness ... Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, …
Matched Mixtures name: … Debiline H …
Matched Categories: … Pepsin A, antagonists & inhibitors …
Collagenase clostridium histolyticum
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Synonyms: … Clostridiopeptidase A …
Matched Description: … [L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA …
Matched Description: … [L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA …
Ixabepilone
Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is...
Approved
Investigational
Matched Synonyms: … Azaepothilone B ... Aza-epothilone B …
Matched Iupac: … (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4- ... yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione …
Matched Description: … Ixabepilone is a semisynthetic analogue of epothilone B. ... Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. ... It has a lactone–lactam modification that minimizes susceptibility to esterase degradation. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4- ... yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione …
Matched Description: … Ixabepilone is a semisynthetic analogue of epothilone B. ... Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. ... It has a lactone–lactam modification that minimizes susceptibility to esterase degradation. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Loxapine
An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Synonyms: … 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine …
Matched Iupac: … 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14 …
Matched Salts cas: … 27833-64-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … ADASUVE 9,1 MG İNHALASYON İÇİN KULLANIMA HAZIR TOZ, 1 ADET …
Matched Iupac: … 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14 …
Matched Salts cas: … 27833-64-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … ADASUVE 9,1 MG İNHALASYON İÇİN KULLANIMA HAZIR TOZ, 1 ADET …
Amoxapine
Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Synonyms: … 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine …
Matched Iupac: … 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative ... In depressed individuals, amoxapine exerts a positive effect on mood. …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic ... Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative ... In depressed individuals, amoxapine exerts a positive effect on mood. …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Nortriptyline
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine ... 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts cas: … 894-71-3 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … methyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Description: … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts cas: … 894-71-3 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …
Estazolam
A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Synonyms: … 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Iupac: … 12-chloro-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ESTA-1 ... ESTA-2 ... ELGRAN-1 …
Matched Iupac: … 12-chloro-9-phenyl-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ESTA-1 ... ESTA-2 ... ELGRAN-1 …
Nirsevimab
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human ... Immunoglobulin g1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal med18897 ... monoclonal antibody.gamma.1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4*01 ( …
Matched Description: … membrane fusion step of the viral entry process, and neutralizes several RSV A and B strains. ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants ... [A254691] This is due to a modification in the Fc region of nirsevimab that grants it a longer half-time …
Matched Categories: … Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody …
Matched Description: … membrane fusion step of the viral entry process, and neutralizes several RSV A and B strains. ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants ... [A254691] This is due to a modification in the Fc region of nirsevimab that grants it a longer half-time …
Matched Categories: … Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody …
Displaying drugs 126 - 150 of 6215 in total