Displaying drugs 1476 - 1500 of 2005 in total
Relmacabtagene autoleucel
Investigational
Matched Synonyms: … AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED ... SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR ENCODING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING OF THE HUMAN …
Priliximab
Investigational
Matched Synonyms: … Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mubodina
Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 …
Matched Description: … It is a recombinant human minibody directed against complement component C5. ... It was investigated in various conditions including primary membranoproliferative glomerulonephritis and …
Matched Description: … It is a recombinant human minibody directed against complement component C5. ... It was investigated in various conditions including primary membranoproliferative glomerulonephritis and …
Regramostim
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107 …
Matched Description: … GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their ... Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their ... Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Vitespen
Investigational
Matched Synonyms: … Endoplasmin (human tumor rejection antigen 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tipapkinogene sovacivec
Investigational
Matched Synonyms: … DNA (synthetic vaccinia virus strain MVA human papillomavirus-targeted) …
PRX-ASL
PRX-ASL is an intracellular enzyme replacement therapy designed to replace the missing or defective enzyme in patients with argininosuccinate lyase deficiency.
Investigational
Matched Synonyms: … Modified messenger ribonucleic acid encoding human argininosuccinate lyase enzyme encapsulated into lipid …
AMT-130
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 5 encoding a microRNA targeted to human Huntingtin gene …
AAV-AIPL
AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human AIPL1 gene. Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in AIPL1 gene.
Investigational
Matched Synonyms: … adenovirus associated viral vector serotype 8 containing the human AIPL1 gene …
Matched Description: … AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. …
Matched Description: … AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. …
CypCaps
Investigational
Matched Synonyms: … Cytochrome P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric …
Dental Mesenchymal Pulp Stem Cells
Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar teeth. Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is...
Investigational
Matched Synonyms: … Allogenic Human Dental Pulp Stem Cells …
Matched Description: … DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 ... DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity ... Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. …
Matched Description: … DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 ... DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity ... Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. …
TOL-101
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zinlirvimab
Zinlirvimab is under investigation in clinical trial NCT03707977 (Dual Bnab Treatment in Children).
Investigational
Matched Synonyms: … Anti-hiv-1 human monoclonal antibody targeting v3 glycan supersite on the hiv-1 envelope protein (10- …
Apamistamab iodine I-131
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD45 antigen) (mus musculus monoclonal BC8 gamma1-chain), disulfide with …
RR001
RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
Matched Synonyms: … autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Dendritic cells vaccine
The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia. With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity, and incomplete viral inactivation.
As...
Investigational
Matched Synonyms: … Recombinant chimeric COVID-19 DC vaccine ... Recombinant chimeric COVID-19 epitope DC vaccine; …
Matched Description: … The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and ... As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials ... With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the …
Matched Description: … The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and ... As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials ... With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the …
VA-MENGOC-BC®
VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C. As there already exists a polysaccharide-based vaccine against meningococcal disease originating from serogroups A,C,W135, and...
Investigational
Matched Synonyms: … Meningococcal polysaccharide vaccine groups B and C …
Matched Description: … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials ... VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. ... The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide …
Matched Description: … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials ... VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. ... The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide …
Prezatide
Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions . Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer...
Experimental
Matched Synonyms: … Growth-modulating peptide (human) …
Matched Description: … Prezatide is used in cosmetic products for the skin and hair. ... and metastatic colon cancer are currently being investigated. ... Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Prezatide is used in cosmetic products for the skin and hair. ... and metastatic colon cancer are currently being investigated. ... Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
SOBI-003
SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients).
Investigational
Matched Synonyms: … Chemically modified recombinant sulfamidase …
Matched Description: … SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. ... It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and …
Matched Description: … SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. ... It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and …
CN-201
CN-201 is a humanized anti-CD3/CD19 bispecific antibody.
Investigational
Matched Synonyms: … recombinant humanized anti-CD3/CD19 bispecific antibody …
OTL-103
Investigational
Matched Synonyms: … Autologous CD34+ cells transfected with lentiviral vector containing the human WAS cDNA (Telethon 003 …
CRS-207
Investigational
Matched Synonyms: … Live-attenuated Listeria monocytogenes actA/inlB/human mesothelin (hMeso) Strain hMeso38 …
RP-A501
RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Danon disease.
Investigational
Matched Synonyms: … Adeno-associated virus serotype 9 vector containing the human lysosome-associated membrane glycoprotein …
Matched Description: … RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9 ... ) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane …
Matched Description: … RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9 ... ) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane …
Ruplizumab
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational
Matched Synonyms: … Recombinant humanized monoclonal antibody 5c8 …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
AAV2/8.TBG.hARSB
Investigational
Matched Synonyms: … serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter driving the expression of the human …
Displaying drugs 1476 - 1500 of 2005 in total