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Displaying drugs 1526 - 1550 of 1800 in total

Nomifensine

Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...

Approved

Withdrawn

Matched Synonyms: … D,L-nomifensine …
Matched Description: … Also withdrawn from the Canadian and UK markets. …

Treprostinil palmitil

Investigational

Matched Synonyms: … 3as,9as)-2-hydroxy-1-((s)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1h-cyclopenta(b)naphthalen-5-yl)oxy)acetate …

6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE

Experimental

Matched Name: … BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE …

Pioglitazone

Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...

Approved

Investigational

Matched Description: … [A19759] Thiazolidinediones, including pioglitazone, have fallen out of favor in recent years due ... , bladder cancer) and the availability of safer and more effective alternatives for patients with type ... Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications …
Matched Mixtures name: … PIOGLITAZONE E METFORMINA DOC ... Pioglitazone and metformin ... Pioglitazone and Metformin Hydrocholride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Matched Products: … MOPRO-D ... Dom-pioglitazone ... PIOGLITAZONE DOC GENERICI …

Obeticholic acid

Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...

Approved

Matched Synonyms: … 6-alpha-ethylchenodeoxycholic acid …
Matched Description: … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... updated its prescribing information to contraindicate the use of obeticholic acid in patients with PBC and ... The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected …
Matched Categories: … Alimentary Tract and Metabolism ... Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy …

Phenylalanine

Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.

Approved

Investigational

Nutraceutical

Matched Synonyms: … (S)-alpha-Amino-beta-phenylpropionic acid …
Matched Description: … essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins …

99mTc-HYNIC (Tyr3)-octreotide

Investigational

Matched Synonyms: … 99mTc-HYNIC-[D-Phe1,Tyr3-Octreotide] …
Matched Iupac: … (99Tc)technetium(5+) 2-({2-[(carboxylatomethyl)amino]ethyl}amino)acetate 4-{[(4R,7S,10S,13R,16S,19R)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Methysergide

An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...

Approved

Matched Synonyms: … 1-Methyl-D-lysergic acid butanolamide ... (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide …
Matched Description: … Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Ergot Alkaloids and Derivatives …

Irpagratinib

Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.

Investigational

Matched Synonyms: … , N-[(3S,4S)-3-[[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d] ... N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin …
Matched Iupac: … N-[(3S,4S)-3-{[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methylazetidin-1-yl)pyrido[3,4-d]pyrimidin …

Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate

Experimental

Matched Name: … Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate …

2-deoxy-2-acetamido-beta-D-galactose-4-sulfate

Experimental

Matched Name: … 2-deoxy-2-acetamido-beta-D-galactose-4-sulfate …

Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate

Experimental

Matched Name: … Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate …

1-Deoxy-1-acetylamino-beta-D-gluco-2-heptulopyranosonamide

Experimental

Matched Name: … 1-Deoxy-1-acetylamino-beta-D-gluco-2-heptulopyranosonamide …

(5-BROMO-4-CHLORO-3-INDOLYL)-A-D-MANNOSE

Experimental

Matched Name: … (5-BROMO-4-CHLORO-3-INDOLYL)-A-D-MANNOSE …

(5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC

Experimental

Matched Name: … (5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC …
Matched Iupac: … 2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}(methyl)amino)ethan-1-ol …