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Displaying drugs 15501 - 15525 of 15971 in total

3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL

Experimental

Tandamine

Tandamine was researched in 1970s as an antidepressant but was never commercialized. Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).
Experimental
Matched Iupac: … (2-{9-ethyl-1-methyl-1H,3H,4H,9H-thiopyrano[3,4-b]indol-1-yl}ethyl)dimethylamine …
Matched Description: … Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI). …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Metralindole

Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A. In Russia, this drug was investigated for potential antidepressant activity.
Experimental
Matched Description: … Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cadazolid

Cadazolid has been used in trials studying the treatment of Clostridium Difficile Infection.
Investigational
Matched Iupac: … 1-cyclopropyl-6-fluoro-7-[4-({2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy}methyl …

Tivantinib

Tivantinib has been investigated in Solid Tumors.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

PSI-697

PSI-697 has been used in trials studying the treatment of Scleritis.
Investigational
Matched Iupac: … 2-[(4-chlorophenyl)methyl]-3-hydroxy-7H,8H,9H,10H-cyclohexa[h]quinoline-4-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

GSK-1292263

GSK1292263 has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.
Investigational
Matched Iupac: … 2-(4-methanesulfonylphenyl)-5-({1-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-4-yl}methoxy)pyridine …
Matched Description: … GSK1292263 has been investigated for the treatment of DIABETES MELLITUS, TYPE 2. …

Indole-3-carbinol

Indole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Iopydol

Experimental

Mepindolol

Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker.
Experimental
Matched Iupac: … 1-[(2-methyl-1H-indol-4-yl)oxy]-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker. …

Obidoxime

Experimental

ATG003

ATG003, a novel anti-angiogenic drug candidate and a formulation of mecamylamine, is currently in clinical development for neovascular age-related macular degeneration.
Investigational
Matched Description: … ATG003, a novel anti-angiogenic drug candidate and a formulation of mecamylamine, is currently in clinical …

Elismetrep

Elismetrep is under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects).
Investigational
Matched Description: … under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and …

Davanat

Davanat is under investigation in clinical trial NCT00054977 (Safety of GM-CT-01 With and Without 5-Fluorouracil in Patients With Solid Tumors).
Investigational
Matched Description: … Davanat is under investigation in clinical trial NCT00054977 (Safety of GM-CT-01 With and Without 5-Fluorouracil …

Proxalutamide

Proxalutamide is under investigation in clinical trial NCT03899467 (The Safety and Tolerability of Proxalutamide (GT0918) in Subjects With Metastatic Castrate Resistant Prostate Cancer).
Investigational
Matched Iupac: … 4-(4,4-dimethyl-3-{6-[3-(1,3-oxazol-2-yl)propyl]pyridin-3-yl}-5-oxo-2-sulfanylideneimidazolidin-1-yl) ... -3-fluoro-2-(trifluoromethyl)benzonitrile …
Matched Description: … Proxalutamide is under investigation in clinical trial NCT03899467 (The Safety and Tolerability of Proxalutamide …

AZD 3355

AZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. It is developed by AstraZeneca and is currently in phase I/II trials.
Investigational
Matched Description: … It is developed by AstraZeneca and is currently in phase I/II trials. …

AZD-4017

AZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
Investigational
Matched Iupac: … 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-(propylsulfanyl)pyridin-2-yl]piperidin-3-yl]acetic acid …
Matched Description: … investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and …

Difamilast

Difamilast is under investigation in clinical trial NCT01702181 (A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis).
Investigational
Matched Iupac: … N-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)-2-ethoxybenzamide …
Matched Description: … Difamilast is under investigation in clinical trial NCT01702181 (A Safety Study to Evaluate the Use and …

Elenbecestat

Elenbecestat is under investigation in clinical trial NCT02956486 (A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Subjects With Early Alzheimer's Disease).
Investigational
Matched Iupac: … -(difluoromethyl)pyrazine-2-carboxamide ... N-{3-[(4aS,5R,7aS)-2-amino-5-methyl-4H,4aH,5H,7H,7aH-furo[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl}-5 …
Matched Description: … Elenbecestat is under investigation in clinical trial NCT02956486 (A 24-Month Study to Evaluate the Efficacy and …

Giripladib

Giripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee).
Investigational
Matched Iupac: … 4-{3-[5-chloro-1-(diphenylmethyl)-2-(2-{[2-(trifluoromethyl)phenyl]methanesulfonamido}ethyl)-1H-indol …
Matched Description: … investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and …

PAS-004

PAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome.
Investigational
Matched Description: … PAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. ... It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome. …

DG041

DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications. DG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor for prostaglandins E2. EP3 is a target that associates with increased risk of various vascular...
Investigational
Matched Description: … DG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor ... first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and …

M0002

M0002 is an orally-active selective vasopressin antagonist that inhibits water re-absorption from the kidneys. It is a vasopressin 2 antagonist and represents a new class of compounds – aquaretics – that produce profound diuresis without loss of electrolytes. It will be of major benefit to those patients not responding satisfactorily...
Investigational
Matched Description: … It is a vasopressin 2 antagonist and represents a new class of compounds – aquaretics – that produce …

CEP-9722

CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
Investigational
Matched Iupac: … -methylpiperazin-1-yl)methyl]-9,19-diazapentacyclo[10.7.0.0^{2,6}.0^{7,11}.0^{13,18}]nonadeca-1(12),2( …
Matched Description: … under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

TRO40303

TRO40303 is under investigation in clinical trial NCT01374321 (Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction).
Investigational
Matched Iupac: … 3-[(3R,3aR,5aS,6R,7E,9aS,9bS)-7-(hydroxyimino)-3a,6-dimethyl-3-[(2R)-6-methylheptan-2-yl]-dodecahydro …
Matched Description: … TRO40303 is under investigation in clinical trial NCT01374321 (Safety and Efficacy Study of TRO40303 …
Displaying drugs 15501 - 15525 of 15971 in total