Displaying drugs 1551 - 1575 of 2005 in total
BREN-02
BREN-02 is a recombinant human homeoprotein Engrailed 1 (rhEN1).
Investigational
Matched Description: … BREN-02 is a recombinant human homeoprotein Engrailed 1 (rhEN1). …
UX053
UX053 is an mRNA encoding the human glycogen debranching enzyme.
Investigational
Matched Description: … UX053 is an mRNA encoding the human glycogen debranching enzyme. …
rhIGFBP-3
rhIGFBP-3 (recombinant human insulin-like growth factor binding protein-3) is Insmed’s proprietary anti-cancer compound that has demonstrated significant decreases in cancerous growth in several models of human. It is developed by Insmed and is currently under phase I of the clinical trial.
Investigational
Matched Description: … It is developed by Insmed and is currently under phase I of the clinical trial. ... compound that has demonstrated significant decreases in cancerous growth in several models of human. ... rhIGFBP-3 (recombinant human insulin-like growth factor binding protein-3) is Insmed’s proprietary anti-cancer …
ACT-101
ACT-101 is a recombinant human alpha-fetoprotein or rhAFP.
Investigational
Matched Description: … ACT-101 is a recombinant human alpha-fetoprotein or rhAFP. …
CCR5 mAb
CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus (HIV-1). It was generated by HGS using the Abgenix XenoMouse technology.
Investigational
Matched Description: … CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor ... CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus (HIV-1). …
INH-A21
INH-A21 is a human staphylococcal immunoglobulin
Investigational
Matched Description: … INH-A21 is a human staphylococcal immunoglobulin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
HGS-TR2J
HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies. It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial.
Investigational
Matched Description: … It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial. ... HGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced …
SIG-205
SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer modified alginate spheres
Investigational
Matched Description: … SIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral ... vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer modified …
(S)-camphor
(S)-camphor, or L(-)-Camphor, is a stereoisomer of DB01744, a bicyclic monoterpene known to potentiate both heat and cold sensations . (S)-camphor is not the naturally-occurring stereoisomer but displays similar TRPV channel affinity and current inhibition . DB01744 is isolated from the wood of the camphor laurel tree, Cinnamomum camphora, and...
Experimental
Matched Description: … by causing sensitization to heat and coolness to relieve minor muscle and joint pain [A33086]. ... It has been used as a nasal decongestant and cough suppressant, and has been topically applied due to ... its antipruritic, analgesic, and counterirritant properties [A33086]. …
CPGJ602
CPGJ602 is a recombinant anti-EGFR human-mouse chimeric monoclonal antibody.
Investigational
Matched Description: … CPGJ602 is a recombinant anti-EGFR human-mouse chimeric monoclonal antibody. …
TBX-1400
TBX-1400 consists of human donor hematopoietic stem and progenitor cells.
Investigational
Matched Description: … TBX-1400 consists of human donor hematopoietic stem and progenitor cells. …
BCX10013
BCX10013 is a small molecule inhibitor of human complement factor D.
Investigational
Matched Description: … BCX10013 is a small molecule inhibitor of human complement factor D. …
Cixutumumab
Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate.
Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like growth factor-I receptor (IGF-IR). IGF-IR is overexpressed in a variety of...
Investigational
Matched Description: … the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and ... Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Theralizumab
Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational
Matched Description: … After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human ... Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Eritoran
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
LYT-200
LYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9.
Investigational
Matched Description: … LYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9. …
HMI-204
HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A
Investigational
Matched Description: … HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A …
AVB-101
AVB-101 is a recombinant AAV9 vector encoding the human progranulin (PGRN) gene.
Investigational
Matched Description: … AVB-101 is a recombinant AAV9 vector encoding the human progranulin (PGRN) gene. …
ASP-7317
ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells.
Investigational
Matched Description: … ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells. …
Humanized monoclonal antibody Hu1B7
Investigational
AVI-014
AVI-014 is a glycosylated, recombinant human granulocyte colony-stimulating factor (G-CSF).
Investigational
Matched Description: … AVI-014 is a glycosylated, recombinant human granulocyte colony-stimulating factor (G-CSF). …
BI-1206
BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b.
Investigational
Matched Description: … BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b. …
TPCA-1
TPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).
Investigational
Matched Description: … TPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152] …
GSK-923295
GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline (GSK). GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of...
Investigational
Matched Description: … and is currently in Phase I human clinical trials being conducted by GSK. ... in nude mice, including models of colon, breast, ovarian, lung and other tumors. ... 923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and …
MANF
MANF is a human recombinant mesencephalic, astrocyte-derived neurotrophic factor.
Investigational
Matched Description: … MANF is a human recombinant mesencephalic, astrocyte-derived neurotrophic factor. …
Displaying drugs 1551 - 1575 of 2005 in total