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Displaying drugs 1551 - 1575 of 2030 in total
CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational
Matched Synonyms: … Chimeric (human-murine) G250 IgG monoclonal antibody …
Matched Description: … an antigen expressed in 95% of clear cell renal cell carcinomas (RCC). ... Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Recombinant human basic fibroblast growth factor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Preparations for Treatment of Wounds and Ulcers …
Recombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction).
Investigational
Matched Synonyms: … Recombinant human lecithin:cholesterol acyltransferase …
Matched Description: … (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction ... Recombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 …
Investigational
Matched Synonyms: … Recombinant Human MG53 protein …
Investigational
Matched Synonyms: … Humanized Igg4 Monoclonal Antibody Binding To Human C1Q …
Investigational
Matched Synonyms: … Adenoviral vector-RheoSwitch Therapeutic System-human interleukin 12 …
Investigational
Matched Synonyms: … Lentiviral Vector Expressing Human Fumarylacetoacetate Hydrolase …
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Synonyms: … Anti-CD134 human monoclonal antibody (IgG1, KHK4083 dimer) …
Matched Description: … In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... injection reactions such as fever and chills have been reported. ... results, the long-term safety of rocatinlimab requires further investigation, as serious adverse events and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
Investigational
Matched Synonyms: … Optimised human arginase I ... Co-ArgI-PEG modified human arginase I …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … Human somatomedin C ... INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues …
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN
Investigational
Matched Synonyms: … Tumor-selective delta-24 ,rgd modified adenovirus serotype 5 …
Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa).
Investigational
Matched Synonyms: … Human monoclonal antibody directed against serotype 011 Pseudomonas aeruginosa ... Human monoclonal antibody directed against serotype O1 Pseudomonas aeruginosa …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
Investigational
Matched Name: … Allogenic fetal mesenchymal stem cells
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ΔΈ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human ... Immunoglobulin g1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal med18897 ... monoclonal antibody.gamma.1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4*01 ( …
Matched Description: … neutralizes several RSV A and B strains. ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants ... the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry process, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Approved
Investigational
Matched Description: … been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and
Matched Products: … GLIANIMON PIP FL …
Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Synonyms: … Insects (whole body), mite dermatophagoides farinae …
Matched Mixtures name: … Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix Dermatophagoides farinae and Dermatophagoides pteronyssinus ... Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 10000 AU per mL …
Matched Categories: … Cell-mediated Immunity …
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Mucocutaneous Epithelial Cell Growth Factor …
Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational
Matched Synonyms: … Pptimized human tissue-type plasminogen activator …
Tarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)).
Investigational
Matched Synonyms: … growth factor A) (human-Mus musculus monoclonal OG1950 g1-chain), disulfide with human-Mus musculus ... Immunoglobulin G1 [240-alanine,241-alanine,243-alanine,449-cysteine], anti-(human vascular endothelial …
Matched Description: … Tarcocimab tedromer is under investigation in clinical trial NCT06270836 (A Study to Evaluate the Efficacy and
MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins known as the anthrax protective antigen.
Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN MONOCLONAL 5E8 LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN, ANTI-(BACILLUS ANTHRACIS ANTHRAX PROTECTIVE ANTIGEN) (HUMAN MONOCLONAL 5E8 HEAVY CHAIN …
Matched Description: … humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal toxins ... MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in …
Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Synonyms: … HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(PROTEIN NOGO-A) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH …
Matched Description: … has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …
Displaying drugs 1551 - 1575 of 2030 in total