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Displaying drugs 1601 - 1625 of 2955 in total
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Acid maltase ... Acid-alpha glucosidase ... Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … 5-(4-carboxymethyl-phenylazo)-2-hydroxy-benzoic acid ... 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid ... Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)- …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid ... glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Acids, Carbocyclic …
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid ... Vinyl gamma-aminobutyric acid ... gamma-Vinyl-gamma-aminobutyric acid
Matched Iupac: … 4-aminohex-5-enoic acid
Matched Description: … the central nervous system, used in the treatment of refractory seizures and infantile spasms. ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was ... [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acid Derivatives …
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched International brands: … Sheng Ao ... Sheng Min …
Matched Description: … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone …
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Synonyms: … Etodolic acid ... (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Heterocyclic ... Indoleacetic Acids
Experimental
Matched Synonyms: … 3-(10-methyl-9-anthryl)propionic acid ... 3-(10-METHYL-ANTHRACEN-9-YL)-PROPIONIC ACID
Matched Name: … 3-(10-methyl-9-anthryl)propanoic acid
Matched Iupac: … 3-(10-methylanthracen-9-yl)propanoic acid
A thiol-containing non-essential amino acid that is oxidized to form cystine.
Approved
Nutraceutical
Matched Synonyms: … (2R)-2-amino-3-mercaptopropanoic acid ... (2R)-2-amino-3-sulfanylpropanoic acid ... (R)-2-Amino-3-mercaptopropanoic acid
Matched Iupac: … (2R)-2-amino-3-sulfanylpropanoic acid
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form cystine. …
Matched Mixtures name: … Premasol - sulfite-free (Amino Acid) ... Premasol - sulfite-free (Amino Acid) ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur ... Proteinogenic Amino Acids
Experimental
Matched Synonyms: … 2S,3S-3-methylaspartic acid ... (3S)-3-methyl-L-aspartic acid
Matched Name: … threo-3-methyl-L-aspartic acid
Matched Iupac: … (2S,3S)-2-amino-3-methylbutanedioic acid
Experimental
Matched Name: … p-Hydroxymercuribenzoic acid
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Name: … M-Aminophenylboronic Acid
Matched Iupac: … (3-aminophenyl)boronic acid
Experimental
Matched Name: … Phenylethane Boronic Acid
Matched Iupac: … (2-phenylethyl)boronic acid
Matched Categories: … Acids ... Acids, Noncarboxylic …
Experimental
Matched Name: … 1-Aminocyclopropanecarboxylic Acid
Matched Iupac: … 1-aminocyclopropane-1-carboxylic acid
Experimental
Matched Name: … 2-Aminoethanimidic Acid
Experimental
Matched Name: … 2-Aminopropanedioic Acid
Matched Iupac: … 2-aminopropanedioic acid
Glutamic acid is the most common excitatory neurotransmitter in the central nervous system.
Experimental
Matched Name: … D-Glutamic Acid
Matched Iupac: … (2R)-2-aminopentanedioic acid
Matched Description: … Glutamic acid is the most common excitatory neurotransmitter in the central nervous system. …
Experimental
Matched Name: … Adenosine Phosphonoacetic Acid
Matched Iupac: … 2-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}-2-oxoethyl)phosphonic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Name: … Acetylamino-Acetic Acid
Matched Iupac: … 2-acetamidoacetic acid
Experimental
Matched Name: … 2-Phosphoglycolic Acid
Matched Iupac: … 2-(phosphonooxy)acetic acid
Experimental
Matched Name: … 5-Fluorolevulinic Acid
Matched Iupac: … 5-fluoro-4-oxopentanoic acid
Matched Categories: … Keto Acids ... Carboxylic Acids
Experimental
Matched Name: … Glutathione sulfonic acid
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfoethyl]carbamoyl}butanoic acid
Experimental
Matched Synonyms: … (6R,2'S)-Folinic acid ... Dextrofolinic acid ... L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] …
Matched Name: … (6R)-Folinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Categories: … Folic Acid and Derivatives …
Experimental
Matched Name: … 2,6-Diaminopimelic Acid
Matched Iupac: … (2S,6S)-2,6-diaminoheptanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Pimelic Acids ... Carboxylic Acids
Experimental
Matched Name: … Beta-Hydroxyaspartic Acid
Matched Iupac: … (2S,3R)-2-amino-3-hydroxybutanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Excitatory Amino Acids ... Amino Acids, Dicarboxylic …
Experimental
Matched Name: … Carbazole Butanoic Acid
Matched Iupac: … 4-(9H-carbazol-9-yl)butanoic acid
Displaying drugs 1601 - 1625 of 2955 in total