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Displaying drugs 1601 - 1625 of 1990 in total

SBT101

SBT101 is a non-replicating recombinant adeno-associated virus serotype 9 (AAV9) gene therapy vector containing the human adenosine triphosphate (ATP)-binding cassette (ABC) sub-family D member 1 (ABCD1) gene.
Investigational
Matched Description: … SBT101 is a non-replicating recombinant adeno-associated virus serotype 9 (AAV9) gene therapy vector ... containing the human adenosine triphosphate (ATP)-binding cassette (ABC) sub-family D member 1 (ABCD1 …

MLN8054

MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
Investigational
Matched Description: … trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and …

(S)-camphor

(S)-camphor, or L(-)-Camphor, is a stereoisomer of DB01744, a bicyclic monoterpene known to potentiate both heat and cold sensations . (S)-camphor is not the naturally-occurring stereoisomer but displays similar TRPV channel affinity and current inhibition . DB01744 is isolated from the wood of the camphor laurel tree, Cinnamomum camphora, and...
Experimental
Matched Description: … by causing sensitization to heat and coolness to relieve minor muscle and joint pain [A33086]. ... It has been used as a nasal decongestant and cough suppressant, and has been topically applied due to ... its antipruritic, analgesic, and counterirritant properties [A33086]. …

Lixmabegagene relduparvovec

Lixmabegagene relduparvovec, formerly known as LYS-GM101, is a recombinant adeno-associated virus vector serotype rh.10 (AAVrh.10) carrying the human β-galactosidase gene (GBL1). It is under development for the treatment of GM1 gangliosidosis.
Experimental
Matched Description: … serotype rh.10 (AAVrh.10) carrying the human β-galactosidase gene (GBL1). ... Lixmabegagene relduparvovec, formerly known as LYS-GM101, is a recombinant adeno-associated virus vector …

Prolease-r-hFSH

Prolease-r-hFSH is a recombinant human follicle stimulating hormone (r-hFSH) with Alkermes' ProLease injectable sustained release drug delivery technology. It provides patients with long term therapeutic benefit from a single administration rather than multiple injections.
Investigational
Matched Description: … Prolease-r-hFSH is a recombinant human follicle stimulating hormone (r-hFSH) with Alkermes' ProLease …

CDX-1135

CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex). It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage.
Investigational
Matched Description: … CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed ... It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage. …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …

Timdarpacept

IMM01 is a recombinant human signal regulatory protein α (SIRPα) IgG 1 fusion protein. IMM01 is under investigation in clinical trial NCT05140811 (A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Investigational
Matched Description: … IMM01 is a recombinant human signal regulatory protein α (SIRPα) IgG 1 fusion protein. ... trial NCT05140811 (A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and …

ARX201

ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino acid (ahGH). ARX201 has improved pharmacological...
Investigational
Matched Description: … ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s ... technology to achieve precise spatial positioning of the site of polyethylene glycol (PEG) attachment to human …

Omburtamab

CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours.[A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers. Omburtamab is under investigation in clinical trial NCT03275402 (131i-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous...
Investigational
Matched Description: … CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours ... [A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are …

Cixutumumab

Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate. Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like growth factor-I receptor (IGF-IR). IGF-IR is overexpressed in a variety of...
Investigational
Matched Description: … Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like ... the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

BBM-H803

BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed. It consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene.
Investigational
Matched Description: … and manufactured by Belief BioMed. ... BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed ... It consists of an adeno-associated virus vector containing an expression cassette of the human Factor …

Arachidonic Acid

An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes,...
Experimental
Matched Description: … It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent ... , thromboxanes, and leukotrienes. ... It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins …
Matched Mixtures name: … SIMILAC ALIMENTUM 400 G TOZ …

Abacavir hydroxyacetate

Prurisol is under investigation for the treatment of Chronic Stable Plaque Psoriasis. Prurisol has been investigated for the treatment of Plaque Psoriasis.
Investigational
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor …

C31G

C31G is a potent broad spectrum antimicrobial agent, effective against gram positive and gram negative bacteria, yeast and fungi.C31G, vaginal gel is developed by Biosyn Inc. and has commenced enrollment in a phase III pivotal clinical trial for the reduction of sexual transmission of human immunodeficiency virus (HIV).
Investigational
Matched Description: … in a phase III pivotal clinical trial for the reduction of sexual transmission of human immunodeficiency ... bacteria, yeast and fungi.C31G, vaginal gel is developed by Biosyn Inc. and has commenced enrollment ... C31G is a potent broad spectrum antimicrobial agent, effective against gram positive and gram negative …

Queuine

Queuine is a derivative of 7-Deazaguanine. Bacteria possess the exclusive ability to synthesize queuine, which is then salvaged and passed on to plants and animals. Quantities of queuine have been found in tomatoes, wheat, coconut water, and milk from humans, cows, and goats. Humans salvage and recover queuine from either...
Experimental
Nutraceutical
Matched Description: … and goats. ... plants and animals. ... Humans salvage and recover queuine from either ingested food or the gut flora. …

SynOV1.1

SynOV1.1 is an investigational cancer immunotherapy developed by SyngenTech. It is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF). SynOV1.1 is under investigation in clinical trial NCT04612504 (Synov1.1 Intratumoral Injection Study).
Investigational
Matched Description: … It is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating …

Albinterferon Alfa-2B

Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human...
Investigational
Matched Description: … Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range ... In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they ... Human Genome Sciences is developing Albuferon as a potential treatment for chronic hepatitis C. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …

Calcium

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the...
Nutraceutical
Matched Description: … Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, ... Calcium gluconate and calcium lactate are absorbed well by pregnant women. ... Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. …
Matched Mixtures name: … CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADET ... Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET …
Matched Categories: … Antacids and Adsorbents ... Alimentary Tract and Metabolism ... multivitamins and calcium ... ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents …
Matched Products: … Tall G U …

Gavocabtagene autoleucel

Gavocabtagene autoleucel is a novel cell therapy consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human Mesothelin, fused to the CD3-epsilon subunit which, upon expression, is incorporated into the endogenous T cell receptor (TCR) complex.
Investigational
Matched Description: … consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human …

AG-702

AG-702 is a recombinant human heat shock protein also known as stress protein. It is also known as HSPs, which are a group of proteins that are induced when a cell undergoes various types of environmental stresses like heat, cold and oxygen deprivation. HSPs are present in all cells in...
Investigational
Matched Description: … AG-702 is a recombinant human heat shock protein also known as stress protein. ... HSPs are present in all cells in all life forms from bacteria to mammals, and their structure and function ... This drug is developed by antigenics for the treatment of genital herpes infection and is under phase …

Adecatumumab

Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM). EpCAM (CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and lung cancer.
Investigational
Matched Description: … Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity ... high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

IMGN632

Investigational

humanized SMART Anti-IL-12 Antibody

The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational

VCN-01

VCN-01 is an investigational, genetically modified human adenovirus encoding human PH20.
Investigational
Matched Description: … VCN-01 is an investigational, genetically modified human adenovirus encoding human PH20. …

AVB-001

AVB-001 is an encapsulated, engineered human ARPE-19 cell line that constitutively expresses the native human IL-2 cytokine
Investigational
Matched Description: … human IL-2 cytokine ... AVB-001 is an encapsulated, engineered human ARPE-19 cell line that constitutively expresses the native …
Displaying drugs 1601 - 1625 of 1990 in total