Displaying drugs 1651 - 1675 of 1990 in total
Disitamab vedotin
Disitamab vedotin is an antibody-drug conjugate drug targeting human epidermal growth factor receptor 2 (HER2). It is currently being investigated for cancers.
Investigational
Matched Description: … Disitamab vedotin is an antibody-drug conjugate drug targeting human epidermal growth factor receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
OCU400
OCU400 is a novel gene therapy comprising an adeno-associated viral vector expressing human nuclear hormone receptor subfamily 2 group E member 3 (hNR2E3).
Investigational
Matched Description: … OCU400 is a novel gene therapy comprising an adeno-associated viral vector expressing human nuclear hormone …
ASC-618
ASC-618 is a recombinant adeno-associated virus serotype 8 (rAAV2/8) vector expressing bioengineered B domain deleted liver-codon-optimized human factor VIII.
Investigational
Matched Description: … adeno-associated virus serotype 8 (rAAV2/8) vector expressing bioengineered B domain deleted liver-codon-optimized human …
Ethylmorphine
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Description: … A narcotic analgesic and antitussive. ... It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
R-851
R-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually...
Investigational
Matched Description: … the human body's immnune system to attack virus-infected cells and tumor cells. ... It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus ... R-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate …
MOR-22
MOR-22, a Natural human lymphoblastoid interferon-alpha, is currently being investigated to treat papillomavirus warts in the oral cavity of HIV-positive patients.
Investigational
Matched Description: … MOR-22, a Natural human lymphoblastoid interferon-alpha, is currently being investigated to treat papillomavirus …
ADVM-062
ADVM-062 is an adeno-associated virus vector carrying complementary deoxyribonucleic acid encoding the human long-wave-sensitive opsin 1 (AAV.7m8-L-opsin)
Investigational
Matched Description: … ADVM-062 is an adeno-associated virus vector carrying complementary deoxyribonucleic acid encoding the human …
Elsamitrucin
The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor models of murine and human origin. (PMID: 8150873)
Investigational
Matched Description: … human origin. ... agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor models of murine and …
SAR422459
SAR422459 is a Lentiviral Vector Containing The Human Abca4 Gene that is currently being investigated to treat Stargardt disease.
Investigational
Matched Description: … SAR422459 is a Lentiviral Vector Containing The Human Abca4 Gene that is currently being investigated …
(R)-warfarin
Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Matched Description: … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared …
Matched Categories: … Warfarin and isomers …
Matched Categories: … Warfarin and isomers …
AVR-RD-02
AVR-RD-02 is an investigational ex vivo lentiviral gene therapy developed by AVROBIO Inc. It consists of autologous CD34+ enriched hematopoietic stem cells (HSCs) that have been genetically modified ex vivo with a lentiviral vector (LV) to contain a ribonucleic acid (RNA) transcript that, after reverse transcription, results in codon-optimized, complementary...
Investigational
Matched Description: … genome, encodes for functional human glucocerebrosidase (GCase). ... results in codon-optimized, complementary deoxyribonucleic acid (cDNA) that, upon its integration into human …
Albinterferon Alfa-2B
Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human...
Investigational
Matched Description: … In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they ... Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range ... Human Genome Sciences is developing Albuferon as a potential treatment for chronic hepatitis C. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Fluorescein lisicol
Fluorescein lisicol has been used in trials studying the diagnostic of Pharmacokinetics, Hepatic Cirrhosis, Hepatitis, Viral, Human, Nonalcoholic Steatohepatitis, and Non-Alcoholic Fatty Liver Disease.
Investigational
Matched Description: … , Nonalcoholic Steatohepatitis, and Non-Alcoholic Fatty Liver Disease. ... been used in trials studying the diagnostic of Pharmacokinetics, Hepatic Cirrhosis, Hepatitis, Viral, Human …
ALM201
ALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. It is being investigated in the treatment of various cancers.
Investigational
Matched Description: … ALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. …
Apatorsen
Apatorsen is a second generation antisense drug which in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human cancers including prostate, lung, breast, ovarian, bladder, renal, pancreatic, multiple myeloma and liver cancer.
Investigational
Matched Description: … cancers including prostate, lung, breast, ovarian, bladder, renal, pancreatic, multiple myeloma and ... production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Iboctadekin
Iboctadekin is under investigation in clinical trial NCT00500058 (A Phase I, Dose-Escalation Study to Assess the Safety and Biological Activity of Recombinant Human Interleukin-18).
Investigational
Matched Description: … Biological Activity of Recombinant Human Interleukin-18). ... investigation in clinical trial NCT00500058 (A Phase I, Dose-Escalation Study to Assess the Safety and …
Neihulizumab
Neihulizumab is a novel immune checkpoint agonistic antibody that binds to human CD162 (PSGL-1), thereby preferentially inducing apoptosis in late stage activated T cells.
Investigational
Matched Description: … Neihulizumab is a novel immune checkpoint agonistic antibody that binds to human CD162 (PSGL-1), thereby …
MB-102 CD123 CAR
MB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.
Investigational
Matched Description: … a truncated human epidermal growth factor receptor. ... genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and …
TAK-611
TAK-611, formerly known as SHP611, is a recombinant human arylsulfatase A. First developed by Takeda, it is being investigated for the treatment of metachromatic leukodystrophy.
Investigational
Matched Description: … TAK-611, formerly known as SHP611, is a recombinant human arylsulfatase A. …
A166
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Stamulumab
MYO-029 is a human anti-GDF-8 monoclonal antibody, which is being developed to treat muscle-wasting diseases including muscular dystrophy and age-related sarcopenia.
Investigational
Matched Description: … including muscular dystrophy and age-related sarcopenia. ... MYO-029 is a human anti-GDF-8 monoclonal antibody, which is being developed to treat muscle-wasting diseases …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
BMS-986012
BMS-986012 is a human antifucosyl-GM1 antibody. It is under investigation in clinical trial NCT02815592 (Trial of BMS-986012 in Combination With Platinum and Etoposide).
Investigational
Matched Description: … BMS-986012 is a human antifucosyl-GM1 antibody. ... under investigation in clinical trial NCT02815592 (Trial of BMS-986012 in Combination With Platinum and …
OBI-999
Investigational
Cenicriviroc
Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.
Investigational
Matched Description: … Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex. ... studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human …
MRx-4DP0004
MRx-4DP0004 is a lyophilised formulation of the Bifidobacterium breve strain of commensal bacteria. It is a live biotherapeutic derived from the microbiota of a healthy human infant.
Investigational
Matched Description: … It is a live biotherapeutic derived from the microbiota of a healthy human infant. …
Displaying drugs 1651 - 1675 of 1990 in total