Displaying drugs 1651 - 1675 of 2029 in total
Rosiglitazone
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched International brands: … Rosit ... Rosix …
Matched Description: … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone …
Matched Description: … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone …
Dihomo-gamma-linolenic acid
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
Investigational
Nutraceutical
Matched International brands: … Tona-lean 1000 CLA …
Matched Description: … A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. …
Matched Salts name: … Sodium dihomo-gamma-linolenate …
Matched Description: … A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. …
Matched Salts name: … Sodium dihomo-gamma-linolenate …
Vitamin A
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina ... It is enriched in the liver, egg yolks, and the fat component of dairy products. …
Matched Mixtures name: … RE FAC-x ... Dark Spot Remover ... Tumee Multi-vitamin …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … OQ - SEE …
Matched Mixtures name: … RE FAC-x ... Dark Spot Remover ... Tumee Multi-vitamin …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … OQ - SEE …
Toralizumab
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Matched Synonyms: … Anti-CD 154 human-mouse monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Edetic acid
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Diet, Food, and Nutrition ... Lead Chelator ... Lead Chelating Activity …
Matched Products: … SODIO EDETATO MONICO ... SODIO EDETATO S.A.L.F. ... SODIO EDETATO GALENICA SENESE …
Matched Categories: … Diet, Food, and Nutrition ... Lead Chelator ... Lead Chelating Activity …
Matched Products: … SODIO EDETATO MONICO ... SODIO EDETATO S.A.L.F. ... SODIO EDETATO GALENICA SENESE …
Calcium Phosphate
Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Approved
Matched Mixtures name: … Milk Calcium With Vitamins C, D, and Phosphorous ... Milk Calcium With Vitamins C, D, and Phosphorous ... Clean Breath Tooth …
Matched Categories: … Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium …
Matched Products: … CALCIO TABLETAS RECUBIERTAS X 600 MG …
Matched Categories: … Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium …
Matched Products: … CALCIO TABLETAS RECUBIERTAS X 600 MG …
Platycodon grandiflorus root
Platycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Campanula Glauca Root …
Interferon beta-1a
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta, recombinant human ... Interferon beta-1a (recombinant human) …
Matched Description: … It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta ... Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Recombinant Human Interferon beta …
Matched Description: … It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta ... Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Recombinant Human Interferon beta …
Bersanlimab
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human intercellular adhesion molecule icam-1) (human monoclonal bi-505 .gamma ... Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human …
Colistin
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … COLISTIMETATO SODICO ALTAN ... COLISTIMETATO SODICO NORIDEM ... COLISTIMETATO SODICO NORIDEM LTD. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … COLISTIMETATO SODICO ALTAN ... COLISTIMETATO SODICO NORIDEM ... COLISTIMETATO SODICO NORIDEM LTD. …
Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these...
Investigational
Matched Name: … Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine …
Matched Description: … (aAPC), and activate T-cells. ... the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and ... Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and …
Matched Description: … (aAPC), and activate T-cells. ... the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and ... Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and …
Retlirafusp alfa
Investigational
Matched Synonyms: … isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal SHR-1316 .kappa. ... programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein with ... Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), anti-(human …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Erythropoietin (recombinant human) ... Erythropoietin (human, recombinant) …
Matched Description: … It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which ... the human erythropoietin gene has been introduced. ... Epoetin alfa formulations can be administered intravenously or subcutaneously. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins ... Hematopoietic Cell Growth Factors ... Increased Erythroid Cell Production …
Matched Products: … ERITROPOYETINA 4.000 U.I X 1 ML ... ERITROPOYETINA HUMANA RECOMBINANTE ... ERITROPOYETINA HUMANA RECOMBINANTE 2000 UI …
Matched Description: … It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which ... the human erythropoietin gene has been introduced. ... Epoetin alfa formulations can be administered intravenously or subcutaneously. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins ... Hematopoietic Cell Growth Factors ... Increased Erythroid Cell Production …
Matched Products: … ERITROPOYETINA 4.000 U.I X 1 ML ... ERITROPOYETINA HUMANA RECOMBINANTE ... ERITROPOYETINA HUMANA RECOMBINANTE 2000 UI …
Peptide YY (1-36)
Investigational
Matched Synonyms: … Peptide YY human ... Peptide YY (human) ... Peptide YY human (1-36) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Ganciclovir
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Description: … Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections. …
Matched Salts name: … Ganciclovir sodium …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … GANCICLOVIR SODIUM FOR INJECTION …
Matched Salts name: … Ganciclovir sodium …
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … GANCICLOVIR SODIUM FOR INJECTION …
Axicabtagene ciloleucel
Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Matched Synonyms: … Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen …
Matched Description: … It is marketed under the brand name Yescarta and is used to treat large B-cell lymphomas and follicular ... CARs that recognize and kill cancer cells, and are infused back into the patient. ... demonstrated that T cells expressing an anti-CD19 CAR can produce cytokines that efficiently kill leukemic …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents ... Genetically-modified Autologous T Cells …
Matched Description: … It is marketed under the brand name Yescarta and is used to treat large B-cell lymphomas and follicular ... CARs that recognize and kill cancer cells, and are infused back into the patient. ... demonstrated that T cells expressing an anti-CD19 CAR can produce cytokines that efficiently kill leukemic …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents ... Genetically-modified Autologous T Cells …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Omidubicel
Omidubicel is a nicotinamide-modified allogeneic hematopoietic progenitor cell therapy derived from cord blood used as an allogeneic stem cell donor source. Umbilical blood cord cells are expanded ex-vivo and nicotinamide (a form of vitamin B3) is used as an active agent in the culture system to inhibit the differentiation and...
Approved
Investigational
Matched Synonyms: … Allogeneic, ex-vivo expanded, umbilical cord blood-derived hematopoietic CD34+ progenitor cells - cultured …
Matched Description: … of hematopoietic stem and progenitor cells. ... Umbilical blood cord cells are expanded _ex-vivo_ and [nicotinamide] (a form of vitamin B3) is used as ... In this group of patients, umbilical cord blood can be used as an alternative cell source since there …
Matched Categories: … Cells, Allogeneic ... Hematopoietic Stem Cells ... Cells, Cultured, Allogeneic ... Allogeneic Cord Blood Hematopoietic Progenitor Cell Therapy …
Matched Description: … of hematopoietic stem and progenitor cells. ... Umbilical blood cord cells are expanded _ex-vivo_ and [nicotinamide] (a form of vitamin B3) is used as ... In this group of patients, umbilical cord blood can be used as an alternative cell source since there …
Matched Categories: … Cells, Allogeneic ... Hematopoietic Stem Cells ... Cells, Cultured, Allogeneic ... Allogeneic Cord Blood Hematopoietic Progenitor Cell Therapy …
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Pegylated human interferon A-2B …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Eftansomatropin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
HUB-101
Investigational
Matched Synonyms: … Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene …
Humate-P
Investigational
Matched Name: … Humate-P …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Allogenic fetal mesenchymal stem cells
Investigational
Matched Name: … Allogenic fetal mesenchymal stem cells …
Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Blood coagulation factor XIV (human) ... Recombinant human activated protein C (rH-APC) …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Description: … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and ... Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Displaying drugs 1651 - 1675 of 2029 in total