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Displaying drugs 1676 - 1700 of 2075 in total

MRK-003

MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5 …
Matched Iupac: … (1'R,3R,10'S)-5-(2,2,2-trifluoroethyl)-5'-[(1E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-en-1-yl]spiro …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …

Sotigalimab

Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Exlinkibart

Investigational
Matched Synonyms: … Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … LOSIL-S ... Cvs ... LOSIL-C …

Brevenal

Investigational
Matched Synonyms: … 2,4-HEPTADIENAL, 7-((2S,3S,4AS,5AR,6AS,7AR,10S,11R,12AS,14AR,15AS,16S,17AR)-11-(3Z)-3,5-HEXADIEN-1-YLEICOSAHYDRO …

9-(6-deoxy-alpha-L-talofuranosyl)-6-methylpurine

Experimental
Matched Name: … 9-(6-deoxy-alpha-L-talofuranosyl)-6-methylpurine …

N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide

Experimental
Matched Name: … N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide …

N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide

N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin.
Experimental
Matched Name: … N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide …
Matched Description: … N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. …

beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide

Experimental
Matched Name: … beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide …

Nanvuranlat

Investigational
Matched Synonyms: … L-tyrosine, o-((5-amino-2-phenyl-7-benzoxazolyl)methyl)-3,5-dichloro- ... O-((5-amino-2-phenyl-1,3-benzoxazol-7-yl)methyl)-3,5- dichloro-l-tyrosine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … RENALAMER CO<sub>3sub> 800 MG FILM TABLET, 180 ADET ... RENVELA(R) TABLETS …

Vorapaxar

Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … ,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto[2,3-c] ... 8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c] ... ,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c] …
Matched Iupac: … 8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho[2,3-c] …
Matched Categories: … Blood and Blood Forming Organs …

(R)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide

Experimental
Matched Name: … (R)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide …

N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide

Experimental
Matched Name: … N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide …

Minnelide free acid

Investigational
Matched Synonyms: … Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl …
Matched Iupac: … ({[(1S,2S,4S,5S,7S,8R,9R,11S,13S)-1-methyl-17-oxo-7-(propan-2-yl)-3,6,10,16-tetraoxaheptacyclo[11.7.0.0 …

Parasorbic acid

Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe berries of the mountain ash.
Experimental
Matched Synonyms: … (S)-(+)-5,6-Dihydro-6-methyl-2H-pyran-2-one …

O-(N-acetyl-alpha-D-galactosaminyl)-L-serine

Experimental
Matched Synonyms: … α-D-GalNAc-Ser …
Matched Name: … O-(N-acetyl-alpha-D-galactosaminyl)-L-serine …

Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine

Experimental
Matched Name: … Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanine …

N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide

Experimental
Matched Name: … N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide …

L-1-naphthyl-2-acetamido-ethane boronic acid

Experimental
Matched Name: … L-1-naphthyl-2-acetamido-ethane boronic acid …

(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

Experimental
Matched Name: … (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene …

L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine

Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …

Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen

Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …

Human blood group H type 1 trisaccharide

Experimental
Matched Synonyms: … α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc ... alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc …

Auranofin

Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity. It has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. Heme oxygenase 1 is...
Approved
Investigational
Matched Synonyms: … 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold …
Matched Description: … Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and …
Matched Categories: … Antiinflammatory and Antirheumatic Products …
Displaying drugs 1676 - 1700 of 2075 in total