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Displaying drugs 1751 - 1775 of 3072 in total
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris;...
Approved
Investigational
Matched Synonyms: … 9(Z)-Retinoic acid ... 9-cis-retinoic acid ... (7E,9Z,11E,13E)-retinoic acid
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth ... An important regulator of gene expression during growth and development, and in neoplasms. ... ; and embryonic development. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Investigational
Matched Synonyms: … 3a,6b,7b,12a-(OH)4-5b-cholanic acid ... (3α,5β,6β,7β,12α)-3,6,7,12-Tetrahydroxycholan-24-oic acid ... 3alpha,6beta,7beta,12alpha-Tetrahydroxy-5beta-cholanoic acid
Matched Name: … 3alpha,6beta,7beta,12alpha-tetrahydroxy-5beta-cholan-24-oic acid
Matched Iupac: … 4-{4,5,7,11-tetrahydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}pentanoic acid
Experimental
Matched Synonyms: … 2S,3S-3-methylaspartic acid ... (3S)-3-methyl-L-aspartic acid
Matched Name: … threo-3-methyl-L-aspartic acid
Matched Iupac: … (2S,3S)-2-amino-3-methylbutanedioic acid
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid ... Vinyl gamma-aminobutyric acid ... gamma-Vinyl-gamma-aminobutyric acid
Matched Iupac: … 4-aminohex-5-enoic acid
Matched Description: … the central nervous system, used in the treatment of refractory seizures and infantile spasms. ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was ... [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acid Derivatives …
Experimental
Matched Synonyms: … 3-(10-methyl-9-anthryl)propionic acid ... 3-(10-METHYL-ANTHRACEN-9-YL)-PROPIONIC ACID
Matched Name: … 3-(10-methyl-9-anthryl)propanoic acid
Matched Iupac: … 3-(10-methylanthracen-9-yl)propanoic acid
Investigational
Matched Synonyms: … Stearic acid, magnesium salt ... Octadecanoic acid, magnesium salt …
Matched Categories: … Fatty Acids
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Acid maltase ... Acid-alpha glucosidase ... Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … 5-(4-carboxymethyl-phenylazo)-2-hydroxy-benzoic acid ... 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid ... Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)- …
Matched Iupac: … 5-[(1E)-2-[4-(carboxymethyl)phenyl]diazen-1-yl]-2-hydroxybenzoic acid
Experimental
Matched Name: … N,N-[2,5-O-dibenzyl-glucaryl]-DI-[valinyl-aminomethanyl-pyridine] …
Experimental
Matched Name: … 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID) …
Matched Iupac: … 5-(dimethylamino)naphthalene-1-sulfonic acid
Investigational
Matched Synonyms: … N'-(7-chloroquinolin-4-yl)-n,n-diethyl-propane-1,3-diamine …
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992. …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Salts name: … Terbinafine hydrochloride
Matched Products: … Terbinafine Hydrochloride ... Terbinafine Hydochloride ... GoodSense Terbinafine Hydrochloride
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Synonyms: … Etodolic acid ... (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Heterocyclic ... Indoleacetic Acids
Dusquetide has been used in trials studying the treatment of Oral Mucositis.
Investigational
Matched Synonyms: … L-arginyl-L-isoleucyl-L-valyl-L-prolyl-L-alanine-amide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … Benzene Hexacarboxylic Acid
Matched Iupac: … benzene-1,2,3,4,5,6-hexacarboxylic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Name: … Methylumbelliferyl sialic acid
Matched Iupac: … hydroxy-2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Experimental
Matched Name: … D-Mannuronic Acid
Matched Iupac: … (2S,3S,4S,5S,6S)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
Experimental
Matched Name: … 4-Carboxycinnamic Acid
Matched Iupac: … 4-[(1E)-2-carboxyeth-1-en-1-yl]benzoic acid
Experimental
Matched Name: … (S)-oxalosuccinic acid
Matched Iupac: … (2S)-1-oxopropane-1,2,3-tricarboxylic acid
The D-isomer of aspartic acid. [PubChem]
Experimental
Matched Name: … D-Aspartic Acid
Matched Iupac: … (2R)-2-aminobutanedioic acid
Matched Description: … The D-isomer of aspartic acid. [PubChem] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Experimental
Matched Name: … 3-Indolebutyric Acid
Matched Iupac: … 4-(1H-indol-3-yl)butanoic acid
Experimental
Matched Name: … 3-Nitrophenylboronic Acid
Matched Iupac: … (3-nitrophenyl)boronic acid
Matched Categories: … Acids ... Acids, Noncarboxylic …
Experimental
Matched Name: … (Carboxyhydroxyamino)Ethanoic Acid
Matched Iupac: … 2-[carboxy(hydroxy)amino]acetic acid
Experimental
Matched Name: … 4-Aminohydrocinnamic Acid
Matched Iupac: … 3-(4-aminophenyl)propanoic acid
Experimental
Matched Name: … 3-Trimethylsilylsuccinic Acid
Matched Iupac: … 2-(trimethylsilyl)butanedioic acid
Displaying drugs 1751 - 1775 of 3072 in total