Displaying drugs 1901 - 1925 of 6866 in total
Dimericine
Investigational
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
Experimental
Matched Iupac: … (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4R,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino ... -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-5-(hydroxymethyl)-3-(2-{[(piperidin-3-yl)methyl]amino}ethoxy …
Afegostat
Experimental
Investigational
Matched Synonyms: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Matched Iupac: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Matched Salts cas: … 919364-56-0 …
Matched Iupac: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Matched Salts cas: … 919364-56-0 …
Lipotecan
Investigational
Matched Synonyms: … ethyl-3,4,12,14-tetrahydro-9-hydroxy-3,14-dioxo-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-4-yl ester ... Propanoic acid, 2-(((2,4,5,7-tetranitro-9h-fluoren-9-ylidene)amino)oxy)-, (4s)-10-((dimethylamino)methyl)-4- …
Matched Iupac: … -[(dimethylamino)methyl]-19-ethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^ ... {4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-19-yl 2-{[(2,4,5,7-tetranitro-9H-fluoren- …
Matched Iupac: … -[(dimethylamino)methyl]-19-ethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^ ... {4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-19-yl 2-{[(2,4,5,7-tetranitro-9H-fluoren- …
(5Z)-3-(4-CHLOROPHENYL)-4-HYDROXY-5-(1-NAPHTHYLMETHYLENE)FURAN-2(5H)-ONE
Experimental
Matched Name: … (5Z)-3-(4-CHLOROPHENYL)-4-HYDROXY-5-(1-NAPHTHYLMETHYLENE)FURAN-2(5H)-ONE …
Matched Iupac: … (5Z)-3-(4-chlorophenyl)-4-hydroxy-5-[(naphthalen-1-yl)methylidene]-2,5-dihydrofuran-2-one …
Matched Iupac: … (5Z)-3-(4-chlorophenyl)-4-hydroxy-5-[(naphthalen-1-yl)methylidene]-2,5-dihydrofuran-2-one …
MX6
MX6 is adamantyl group derivatives containing retinoid-related compounds induce apoptosis of cancer cells and therefore may be used for the treatment of cancer, including advanced cancer. More specifically, it has been shown that such adamantyl compounds, e.g., 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid, 2-[3-(1-adamantyl)-4-methoxyphenyl]-5-benzimidazole carboxylic acid, and 6-[3-(1-adamantyl)-4,5-methylenedioxyphenyl]-2-naphthoic acid, can be used to treat...
Investigational
Matched Description: … ., 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid, 2-[3-(1-adamantyl)-4-methoxyphenyl]-5-benzimidazole ... carboxylic acid, and 6-[3-(1-adamantyl)-4,5-methylenedioxyphenyl]-2-naphthoic acid, can be used to treat …
Tyrphostin AG 555
Experimental
TERT-572
Investigational
(3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL
Experimental
Matched Name: … (3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL …
Matched Iupac: … (3R,4R,5R)-5-(hydroxymethyl)-1-(3-phenylpropyl)piperidine-3,4-diol …
Matched Iupac: … (3R,4R,5R)-5-(hydroxymethyl)-1-(3-phenylpropyl)piperidine-3,4-diol …
Defactinib
Defactinib has been investigated for the treatment of Malignant Pleural Mesothelioma.
Investigational
Matched Synonyms: … N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin …
Matched Iupac: … N-methyl-4-{[4-({[3-(N-methylmethanesulfonamido)pyrazin-2-yl]methyl}amino)-5-(trifluoromethyl)pyrimidin …
Matched Salts cas: … 1073160-26-5 …
Matched Iupac: … N-methyl-4-{[4-({[3-(N-methylmethanesulfonamido)pyrazin-2-yl]methyl}amino)-5-(trifluoromethyl)pyrimidin …
Matched Salts cas: … 1073160-26-5 …
Aldumastat
Investigational
Matched Synonyms: … (5s)-5-cyclopropyl-5-(3-((3s)-4-(3,5-difluorophenyl)-3-methylpiperazin-1-yl)-3- oxopropyl)imidazolidine ... (s)-5-cyclopropyl-5-(3-((s)-4-(3,5-difluorophenyl)-3methylpiperazin-1-yl)-3-oxopropyl)imidazolidine-2,4 ... 2,4-imidazolidinedione, 5-cyclopropyl-5-(3-((3s)-4-(3,5-difluorophenyl)-3-methyl-1-piperazinyl)-3-oxopropyl …
Tavapadon
Tavapadon is under investigation in clinical trial NCT02262767 (A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride in Healthy Subjects).
Investigational
Matched Iupac: … 1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1,2,3,4-tetrahydropyrimidine …
Lumicitabine
Lumicitabine is under investigation in clinical trial NCT03010059 (A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 Different New Concept Formulations (Oral Suspension and Tablet) Compared to Their Respective Current Formulations, and to Assess the Effect of Food on the Pharmacokinetics of the 2 New Concept Formulations).
Investigational
Matched Iupac: … [(2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-2-(chloromethyl)-4-fluoro-3-[(2-methylpropanoyl …
EMB-01
EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Investigational
SEL-24
Investigational
Matched Synonyms: … 1h-benzimidazole, 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)- ... 5,6-dibromo-1-(1-methylethyl)-4-nitro-2-(4-piperidinyl)-1h-benzimidazole ... 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1h-1,3-benzimidazole …
Matched Iupac: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1H-1,3-benzodiazole …
Matched Iupac: … 5,6-dibromo-4-nitro-2-(piperidin-4-yl)-1-(propan-2-yl)-1H-1,3-benzodiazole …
2-methyl-5-methylidenepyrimidin-4-imine
Experimental
Matched Synonyms: … 4-Imino-5-Methidyl-2-Methylpyrimidine ... 2-Methyl-5-methylene-4(5H)-pyrimidinimine …
Matched Name: … 2-methyl-5-methylidenepyrimidin-4-imine …
Matched Iupac: … 2-methyl-5-methylidene-4,5-dihydropyrimidin-4-imine …
Matched Name: … 2-methyl-5-methylidenepyrimidin-4-imine …
Matched Iupac: … 2-methyl-5-methylidene-4,5-dihydropyrimidin-4-imine …
5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one
Experimental
Matched Name: … 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one …
Matched Iupac: … 5,5-dimethyl-2-(morpholin-4-yl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one …
Matched Iupac: … 5,5-dimethyl-2-(morpholin-4-yl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one …
ALS-08
ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic lateral sclerosis (ALS). It is being developed by Avicena Group, Inc.
Investigational
CT-011
CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.
Investigational
ELX-02
ELX-02 is under investigation in clinical trial NCT03309605 (Phase 1 Study of ELX-02 in Healthy Adult Subjects).
Investigational
Matched Iupac: … (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1R)-1-aminoethyl]-3,4 …
AT-001
AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Investigational
Matched Iupac: … 2-(8-oxo-7-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-7H,8H-pyrazino[2,3-d]pyridazin-5-yl)acetic …
CB-010
CB-010 is a CRISPR-edited allogeneic CAR-T cell therapy targeting CD19. It is being investigated for the treatment of follicular lymphoma.
Investigational
EF-022
EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Investigational
VCN-01
VCN-01 is an investigational, genetically modified human adenovirus encoding human PH20.
Investigational
Displaying drugs 1901 - 1925 of 6866 in total