Displaying drugs 2126 - 2150 of 2637 in total
Osimertinib
Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Description: … [A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC ... binding and limiting toxicity. ... Furthermore, osimertinib has been shown to spare wild-type EGFR during therapy, thereby reducing non-specific …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Description: … [A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC ... binding and limiting toxicity. ... Furthermore, osimertinib has been shown to spare wild-type EGFR during therapy, thereby reducing non-specific …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Zafirlukast
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Synonyms: … 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide …
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5 …
Matched Description: … It is available as a tablet and is usually dosed twice daily. ... antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and ... on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and …
Matched Categories: … Sulfones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5 …
Matched Description: … It is available as a tablet and is usually dosed twice daily. ... antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and ... on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and …
Matched Categories: … Sulfones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Scarlet red
Scarlet red is under investigation in clinical trial NCT00591916 (New Treatment for Donor Sites).
Investigational
Matched Synonyms: … 2',3-dimethyl-4-(2-hydroxynaphthylazo) azobenzene …
Matched Description: … Scarlet red is under investigation in clinical trial NCT00591916 (New Treatment for Donor Sites). …
Matched Description: … Scarlet red is under investigation in clinical trial NCT00591916 (New Treatment for Donor Sites). …
Practolol
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Approved
Matched Synonyms: … N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide …
Matched Iupac: … N-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
Matched Iupac: … N-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide …
2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …
Leucovorin
Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Synonyms: … N5-Formyltetrahydrofolic acid ... N5-Formyl-5,6,7,8-tetrahydrofolic acid ... N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid …
Matched Description: … for use in the treatment of megaloblastic anemias due to folic acid deficiency when oral therapy is not ... Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and …
Matched Mixtures name: … NEO CROMATON BICOMPLESSO …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives …
Matched Products: … SULTON …
Matched Description: … for use in the treatment of megaloblastic anemias due to folic acid deficiency when oral therapy is not ... Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and …
Matched Mixtures name: … NEO CROMATON BICOMPLESSO …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives …
Matched Products: … SULTON …
1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine
Experimental
Matched Name: … 1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine …
Matched Iupac: … N-(4-{[3-butyl-2,6-dioxo-1-(prop-2-en-1-yl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}phenyl)acetamide …
Matched Iupac: … N-(4-{[3-butyl-2,6-dioxo-1-(prop-2-en-1-yl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}phenyl)acetamide …
N-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide
Experimental
Matched Name: … N-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide …
Matched Iupac: … N-[(2S)-2-(1H-indol-5-yl)butyl]-4-sulfamoylbenzamide …
Matched Iupac: … N-[(2S)-2-(1H-indol-5-yl)butyl]-4-sulfamoylbenzamide …
N-[(2S)-3-Phenyl-2-sulfanylpropanoyl]-L-phenylalanyl-L-tyrosine
Experimental
Matched Name: … N-[(2S)-3-Phenyl-2-sulfanylpropanoyl]-L-phenylalanyl-L-tyrosine …
N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide
Experimental
Matched Name: … N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide …
Matched Iupac: … N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide …
Matched Iupac: … N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide …
4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
Experimental
Matched Name: … 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 4-chloro-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 4-chloro-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
Experimental
Matched Name: … 3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 3-bromo-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 3-bromo-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
(3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE
Experimental
Matched Name: … (3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide …
Matched Iupac: … (3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide …
N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE
Experimental
Matched Name: … N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE …
(2S)-4-(4-fluorobenzyl)-N-(2-sulfanylethyl)piperazine-2-carboxamide
Experimental
Matched Name: … (2S)-4-(4-fluorobenzyl)-N-(2-sulfanylethyl)piperazine-2-carboxamide …
Matched Iupac: … (2S)-4-[(4-fluorophenyl)methyl]-N-(2-sulfanylethyl)piperazine-2-carboxamide …
Matched Iupac: … (2S)-4-[(4-fluorophenyl)methyl]-N-(2-sulfanylethyl)piperazine-2-carboxamide …
(2S)-4-(4-fluorobenzyl)-N-(3-sulfanylpropyl)piperazine-2-carboxamide
Experimental
Matched Name: … (2S)-4-(4-fluorobenzyl)-N-(3-sulfanylpropyl)piperazine-2-carboxamide …
Matched Iupac: … (2S)-4-[(4-fluorophenyl)methyl]-N-(3-sulfanylpropyl)piperazine-2-carboxamide …
Matched Iupac: … (2S)-4-[(4-fluorophenyl)methyl]-N-(3-sulfanylpropyl)piperazine-2-carboxamide …
(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE
Experimental
Matched Name: … (3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE …
Matched Iupac: … (3R)-3-(fluoromethyl)-N-(3,3,3-trifluoropropyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide …
Matched Iupac: … (3R)-3-(fluoromethyl)-N-(3,3,3-trifluoropropyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide …
(E)-3,4-DIHYDROXY-N'-[(2-METHOXYNAPHTHALEN-1-YL)METHYLENE]BENZOHYDRAZIDE
Experimental
Matched Name: … (E)-3,4-DIHYDROXY-N'-[(2-METHOXYNAPHTHALEN-1-YL)METHYLENE]BENZOHYDRAZIDE …
Matched Iupac: … 3,4-dihydroxy-N'-[(E)-(2-methoxynaphthalen-1-yl)methylidene]benzohydrazide …
Matched Iupac: … 3,4-dihydroxy-N'-[(E)-(2-methoxynaphthalen-1-yl)methylidene]benzohydrazide …
N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine
Experimental
Matched Name: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-
Experimental
Matched Name: … N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO- …
Matched Iupac: … (3R,5S)-N-{4-chloro-3-[(pyridin-3-yloxy)methyl]phenyl}-3-fluoro-5-(morpholin-4-yl)cyclohex-1-ene-1-carboxamide …
Matched Iupac: … (3R,5S)-N-{4-chloro-3-[(pyridin-3-yloxy)methyl]phenyl}-3-fluoro-5-(morpholin-4-yl)cyclohex-1-ene-1-carboxamide …
Neoarsphenamine
Investigational
Withdrawn
Matched Synonyms: … Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate …
N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE
Experimental
Matched Name: … N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE …
Matched Iupac: … N-methyl-N-[(1S,4r)-4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl]acetamide …
Matched Iupac: … N-methyl-N-[(1S,4r)-4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl]acetamide …
N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
Experimental
Matched Name: … N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE …
Diclofenac
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched International brands: … Nu-Diclo …
Matched Description: … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... Panamax Gel ... Panamax Patch 60mg/12g …
Matched Description: … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acetic Acid Derivatives and Related Substances ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... Panamax Gel ... Panamax Patch 60mg/12g …
1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide
Experimental
Matched Name: … 1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide …
Displaying drugs 2126 - 2150 of 2637 in total