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Displaying drugs 2226 - 2250 of 2865 in total
Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic Therapy.
Investigational
Matched Synonyms: … N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester …
Matched Description: … , and Normal Volunteers. ... Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Carbocyclic ... Carboxylic Acids
PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family.[A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin …
Matched Iupac: … 4-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic acid
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family ... [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine …
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … 2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Categories: … simvastatin, acetylsalicylic acid and ramipril ... atorvastatin, acetylsalicylic acid and ramipril ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... ramipril and felodipine …
Experimental
Matched Synonyms: … 5'-Thymidylic acid, 3'-deoxy-3'-fluoro- …
Matched Iupac: … ,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid
Experimental
Matched Synonyms: … carboxymethylamino)-3-[(R)-hydroxy-(N-hydroxy-4-iodoanilino)methyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(R)-hydroxy[hydroxy(4-iodophenyl)amino]methyl]sulfanyl}ethyl]carbamoyl}butanoic acid
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Synonyms: … 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acid
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
NNC-55-0396 is a T-type Ca(2+) channel inhibitor.
Investigational
Matched Synonyms: … Cyclopropanecarboxylic acid, (1s,2s)-2-(2-((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro …
Investigational
Matched Synonyms: … 1,3,5-triazine-1(2h)-propanoic acid, 3-((4-chlorophenyl)methyl)tetrahydro-.alpha. …
Investigational
Matched Synonyms: … Coconut fatty acid diethanolamide …
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
Experimental
Matched Name: … (3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester …
Experimental
Matched Name: … (2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate …
Matched Iupac: … [(2R)-2,3-bis(heptanoyloxy)propoxy]phosphonic acid
Experimental
Matched Name: … 2,3-Bis-Benzo[1,3]Dioxol-5-Ylmethyl-Succinic Acid
Matched Iupac: … (2S,3S)-2,3-bis[(2H-1,3-benzodioxol-5-yl)methyl]butanedioic acid
Experimental
Matched Name: … 8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid
Matched Iupac: … (8S)-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7,8-dihydroquinoline-2-carboxylic acid
Experimental
Matched Name: … 3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester …
Experimental
Matched Name: … PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] …
Experimental
Matched Name: … (3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid
Matched Iupac: … (3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid
Experimental
Matched Name: … 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid
Matched Iupac: … 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid
Experimental
Matched Name: … 1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID
Matched Iupac: … 5-{[(4-nitrophenyl)methyl](phosphonomethyl)amino}pentanoic acid
Experimental
Matched Name: … (1R)-2-PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID
Matched Iupac: … 3-[(2R)-2-(dihydroxyboranyl)-2-(2-phenylacetamido)ethyl]benzoic acid
Experimental
Matched Name: … (2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid
Matched Iupac: … (2R)-2-benzyl-4,4-dihydroxy-5-nitropentanoic acid
Experimental
Matched Name: … 3-(5-methoxy-1H-indol-3-yl)propanoic acid
Matched Iupac: … 3-(5-methoxy-1H-indol-3-yl)propanoic acid
Metabolic product of biphenyl; from Pseudomonas putida.
Experimental
Matched Name: … 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid
Matched Iupac: … (2Z,4E)-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
Matched Categories: … Fatty Acids
Experimental
Matched Name: … 3-[(4-Carboxy-2-hydroxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid
Matched Iupac: … 3-[(4-carboxy-2-hydroxyphenyl)sulfamoyl]thiophene-2-carboxylic acid
Experimental
Matched Name: … (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID
Matched Iupac: … (2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid
Displaying drugs 2226 - 2250 of 2865 in total