Pharmacology of anticoagulants used in the treatment of venous thromboembolism.

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Nutescu EA, Burnett A, Fanikos J, Spinler S, Wittkowsky A

Pharmacology of anticoagulants used in the treatment of venous thromboembolism.

J Thromb Thrombolysis. 2016 Jan;41(1):15-31. doi: 10.1007/s11239-015-1314-3.

PubMed ID

26780737 [ View in PubMed

]

Abstract

Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective therapeutic agents, anticoagulants can also result in hemorrhage and other side effects. Thus, anticoagulant therapy selection should be guided by the risks, benefits and pharmacologic characteristics of each agent for each patient. Safe use of anticoagulants requires not only an in-depth knowledge of their pharmacologic properties but also a comprehensive approach to patient management and education. This paper will summarize the key pharmacologic properties of the anticoagulant agents used in the treatment of patients with VTE.

DrugBank Data that Cites this Article

Drugs

Enoxaparin

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Enoxaparin	Prothrombin	Protein	Humans	Unknown	Inhibitor	Details

Drug Interactions

Drugs	Interaction
Integrate drug-drug interactions in your software
Acenocoumarol Imatinib	Imatinib may increase the anticoagulant activities of Acenocoumarol.
Warfarin Imatinib	Imatinib may increase the anticoagulant activities of Warfarin.