Ritodrine-induced leukopenia: a case report and literature review.

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Wu CD, Chao AS, Cheng PJ, Soong YK

Ritodrine-induced leukopenia: a case report and literature review.

Changgeng Yi Xue Za Zhi. 1996 Dec;19(4):388-91.

PubMed ID

9041773 [ View in PubMed

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Abstract

Ritodrine hydrochloride, a beta 2-adrenergic receptor agonist, has been widely applied in the treatment of premature labor for many years and generally considered as a safe medication. It can however induce some serious side effects, such as pulmonary edema, myocardial ischemia, ketoacidosis, miscellaneous metabolic alterations, and leukopenia. This report presents a rare case of leukopenia in a Chinese woman as a result of low dose continuous intravenous infusion of ritodrine, in which the white blood cell count dropped rapidly and recovered quickly following the cessation of administration. The rapid and spontaneous reversal of leukopenia was most probably due to early recognition and intervention of this drug-induced side effect.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Ritodrine	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details