Structural and functional basis of cyclooxygenase inhibition.

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Blobaum AL, Marnett LJ

Structural and functional basis of cyclooxygenase inhibition.

J Med Chem. 2007 Apr 5;50(7):1425-41. Epub 2007 Mar 7.

PubMed ID

17341061 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Diclofenac	Prostaglandin G/H synthase 2	IC 50 (nM)	20	N/A	N/A	Details
Flurbiprofen	Prostaglandin G/H synthase 2	IC 50 (nM)	10	N/A	N/A	Details
Indomethacin	Prostaglandin G/H synthase 2	IC 50 (nM)	10	N/A	N/A	Details
Lumiracoxib	Prostaglandin G/H synthase 2	IC 50 (nM)	7	N/A	N/A	Details