Nv-52: a novel thromboxane synthase inhibitor for the treatment of inflammatory bowel disease.

Article Details

Citation
Copy to clipboard

Howes LG, James MJ, Florin T, Walker C

Nv-52: a novel thromboxane synthase inhibitor for the treatment of inflammatory bowel disease.

Expert Opin Investig Drugs. 2007 Aug;16(8):1255-66.

PubMed ID
17685873 [ View in PubMed
]
Abstract

NV-52, a synthetic flavonoid derivative, is a selective thromboxane synthase (TXS) inhibitor that is being developed as a treatment for inflammatory bowel disease. NV-52 selectively inhibits TXS in vitro in physiological relevant concentrations, causing a reduction in thromboxane B(2) of

DrugBank Data that Cites this Article

Drugs
Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
NV-52Thromboxane-A synthaseProteinHumans
Unknown
Not AvailableDetails