DB05673ExperimentalSmall molecule
NV-52 is an investigational synthetic flavonoid thromboxane synthase (TXS) inhibitor developed for the maintenance of remission in inflammatory bowel disease.
- Mechanism
- Curator reviewed
NV-52 is a synthetic flavonoid derivative. It is a selective thromboxane synthase (TXS) inhibitor under development for the treatment of inflammatory bowel disease. NV-52 selectively inhibits TXS in vitro in physiological relevant concentrations, causing a reduction in thromboxane B2 of ≤ 40% in association with an increase in prostaglandin E2.
- Primary indication
- Investigated for use/treatment in inflammatory bowel disease.Curator reviewed
- Code names
- NV-52
Resolves to
Targets
What you can answer from here — as of April 02, 2025
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with NV-52, and which of those have an active Phase 3 trial?
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