Vascular endothelial growth factor A, long form

BE0000163ProteinHumansVEGFA

Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed:35455969). It is acted on by 38 drugs in DrugBank.

Gene name
VEGFA
UniProtKB entry
P15692Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
395 residues · 43,597 Da
Also known as
L-VEGF · Vascular permeability factor · VEGF · VPF

Resolves to

Protein
UniProtP15692UniProt nameVEGFA_HUMAN
Gene
HGNCHGNC:12680NCBI Gene7422GenBank181971GeneCardsVEGFA
Pharmacology
KEGGhsa:7422
Structure
PDB1BJ1PDB1CZ8PDB1FLT
Drugs

What you can answer from here — as of September 03, 2024

38DrugsApproved to experimental, with action, bond type and pharmacological action
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76Clinical trialsTrials of drugs acting on it, by phase and status
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41GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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110+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Vascular endothelial growth factor A, long form, how selective are they, and which programs against it are still in active trials?

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