Plasminogen activator inhibitor 1

BE0000240ProteinHumansSERPINE1

Serine protease inhibitor. It is acted on by 13 drugs in DrugBank.

Gene name
SERPINE1
UniProtKB entry
P05121Swiss-Prot
Cellular location
Secreted
Residues / weight
402 residues · 45,060 Da
Also known as
Endothelial plasminogen activator inhibitor · PAI · PAI-1 · PAI1 · PLANH1

Resolves to

Protein
UniProtP05121UniProt namePAI1_HUMAN
Gene
HGNCHGNC:8583NCBI Gene5054GenBank35272GeneCardsSERPINE1
Pharmacology
KEGGhsa:5054
Structure
PDB1A7CPDB1B3KPDB1C5G
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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50+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Plasminogen activator inhibitor 1, how selective are they, and which programs against it are still in active trials?

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