Pancreatic triacylglycerol lipase

BE0000683ProteinHumansPNLIP

Plays an important role in fat metabolism. It is acted on by 23 drugs in DrugBank.

Gene name
PNLIP
UniProtKB entry
P16233Swiss-Prot
Cellular location
Secreted
Residues / weight
465 residues · 51,156 Da
Also known as
3.1.1.3 · Pancreatic lipase · PL · PTL

Resolves to

Protein
UniProtP16233UniProt nameLIPP_HUMAN
Gene
HGNCHGNC:9155NCBI Gene5406GenBank339597GeneCardsPNLIP
Pharmacology
IUPHAR/GtoPdb2590KEGGhsa:5406
Structure
PDB1GPLPDB1LPAPDB1LPB
Drugs

What you can answer from here — as of September 07, 2019

23DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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63+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Pancreatic triacylglycerol lipase, how selective are they, and which programs against it are still in active trials?

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