Vitamin K epoxide reductase complex subunit 1

BE0000713ProteinHumansVKORC1

Involved in vitamin K metabolism. It is acted on by 13 drugs in DrugBank.

Gene name
VKORC1
UniProtKB entry
Q9BQB6Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
163 residues · 18,234 Da
Also known as
1.17.4.4 · Vitamin K1 2,3-epoxide reductase subunit 1 · VKOR

Resolves to

Protein
UniProtQ9BQB6UniProt nameVKOR1_HUMAN
Gene
HGNCHGNC:23663NCBI Gene79001GenBank40217983GeneCardsVKORC1
Pharmacology
IUPHAR/GtoPdb2645KEGGhsa:79001
Structure
PDB6WV3PDB6WV4PDB6WV5
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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68+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Vitamin K epoxide reductase complex subunit 1, how selective are they, and which programs against it are still in active trials?

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