Osteocalcin

BE0000724ProteinHumansBGLAP

The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein (PubMed:3019668, PubMed:6967872). It is acted on by 3 drugs in DrugBank.

Gene name
BGLAP
UniProtKB entry
P02818Swiss-Prot
Cellular location
Secreted
Residues / weight
100 residues · 10,962 Da
Also known as
BGP · Bone Gla protein · Gamma-carboxyglutamic acid-containing protein

Resolves to

Protein
UniProtP02818UniProt nameOSTCN_HUMAN
Gene
HGNCHGNC:1043NCBI Gene632GenBank36093GeneCardsBGLAP
Pharmacology
KEGGhsa:632
Structure
PDB8XS1PDB9BURPDB9BUX
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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28GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Osteocalcin, how selective are they, and which programs against it are still in active trials?

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