Glucagon-like peptide 1 receptor

BE0000857ProteinHumansGLP1R

G protein-coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449, PubMed:7517895, PubMed:8216285, PubMed:8405712). It is acted on by 33 drugs in DrugBank.

Gene name
GLP1R
UniProtKB entry
P43220Swiss-Prot
Cellular location
Cell membrane
Residues / weight
463 residues · 53,025 Da
Also known as
GLP-1 receptor · GLP-1-R · GLP-1R

Resolves to

Protein
UniProtP43220UniProt nameGLP1R_HUMAN
Gene
HGNCHGNC:4324NCBI Gene2740GenBank405082GeneCardsGLP1R
Pharmacology
IUPHAR/GtoPdb249KEGGhsa:2740
Structure
PDB3C59PDB3C5TPDB3IOL
Drugs

What you can answer from here — as of September 07, 2019

33DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
154+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Glucagon-like peptide 1 receptor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In