Lactotransferrin

BE0000994ProteinHumansLTF

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is acted on by 11 drugs in DrugBank.

Gene name
LTF
UniProtKB entry
P02788Swiss-Prot
Cellular location
Secreted
Residues / weight
710 residues · 78,181 Da
Also known as
3.4.21.- · GIG12 · Growth-inhibiting protein 12 · Lactoferrin · LF

Resolves to

Protein
UniProtP02788UniProt nameTRFL_HUMAN
Gene
HGNCHGNC:6720NCBI Gene4057GenBank34416GeneCardsLTF
Pharmacology
KEGGhsa:4057
Structure
PDB1B0LPDB1BKAPDB1CB6
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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86+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Lactotransferrin, how selective are they, and which programs against it are still in active trials?

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