Peroxisome proliferator-activated receptor delta

BE0001007ProteinHumansPPARD

Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues (PubMed:35675826). It is acted on by 31 drugs in DrugBank.

Gene name
PPARD
UniProtKB entry
Q03181Swiss-Prot
Cellular location
Nucleus
Residues / weight
441 residues · 49,903 Da
Also known as
NR1C2 · NUC1 · NUCI · Nuclear hormone receptor 1 · Nuclear receptor subfamily 1 group C member 2

Resolves to

Protein
UniProtQ03181UniProt namePPARD_HUMAN
Gene
HGNCHGNC:9235NCBI Gene5467GenBank190230GeneCardsPPARD
Pharmacology
IUPHAR/GtoPdb594KEGGhsa:5467
Structure
PDB1GWXPDB1Y0SPDB2AWH
Drugs

What you can answer from here — as of September 07, 2019

31DrugsApproved to experimental, with action, bond type and pharmacological action
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44GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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99+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peroxisome proliferator-activated receptor delta, how selective are they, and which programs against it are still in active trials?

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