G protein-activated inward rectifier potassium channel 1

BE0001028ProteinHumansKCNJ3

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. It is acted on by 9 drugs in DrugBank.

Gene name
KCNJ3
UniProtKB entry
P48549Swiss-Prot
Cellular location
Membrane
Residues / weight
501 residues · 56,603 Da
Also known as
GIRK-1 · GIRK1 · Inward rectifier K(+) channel Kir3.1 · Potassium channel, inwardly rectifying subfamily J member 3

Resolves to

Protein
UniProtP48549UniProt nameKCNJ3_HUMAN
Gene
HGNCHGNC:6264NCBI Gene3760GenBank1055028GeneCardsKCNJ3
Pharmacology
IUPHAR/GtoPdb434KEGGhsa:3760
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
12GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
20+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on G protein-activated inward rectifier potassium channel 1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In