G protein-activated inward rectifier potassium channel 2

BE0001030ProteinHumansKCNJ6

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. It is acted on by 5 drugs in DrugBank.

Gene name
KCNJ6
UniProtKB entry
P48051Swiss-Prot
Cellular location
Membrane
Residues / weight
423 residues · 48,451 Da
Also known as
BIR1 · GIRK-2 · GIRK2 · Inward rectifier K(+) channel Kir3.2 · KATP-2

Resolves to

Protein
UniProtP48051UniProt nameKCNJ6_HUMAN
Gene
HGNCHGNC:6267NCBI Gene3763GenBank1052875GeneCardsKCNJ6
Pharmacology
IUPHAR/GtoPdb435KEGGhsa:3763
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
15+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on G protein-activated inward rectifier potassium channel 2, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In