Protein S100-B

BE0001177ProteinHumansS100B

Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain (PubMed:20950652, PubMed:6487634). It is acted on by 11 drugs in DrugBank.

Gene name
S100B
UniProtKB entry
P04271Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
92 residues · 10,713 Da
Also known as
S-100 protein beta chain · S-100 protein subunit beta · S100 calcium-binding protein B

Resolves to

Protein
UniProtP04271UniProt nameS100B_HUMAN
Gene
HGNCHGNC:10500NCBI Gene6285GenBank337730GeneCardsS100B
Pharmacology
KEGGhsa:6285
Structure
PDB1MQ1PDB1UWOPDB2H61
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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27GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein S100-B, how selective are they, and which programs against it are still in active trials?

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