Tubulin beta-4A chain

BE0001408ProteinHumansTUBB4A

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. It is acted on by 5 drugs in DrugBank.

Gene name
TUBB4A
UniProtKB entry
P04350Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
444 residues · 49,585 Da
Also known as
TUBB4 · TUBB5 · Tubulin 5 beta · Tubulin beta-4 chain

Resolves to

Protein
UniProtP04350UniProt nameTBB4A_HUMAN
Gene
HGNCHGNC:20774NCBI Gene10382GenBank35959GeneCardsTUBB4A
Pharmacology
KEGGhsa:10382
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tubulin beta-4A chain, how selective are they, and which programs against it are still in active trials?

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