Glucosamine-6-phosphate deaminase

BE0001626ProteinEscherichia coli (strain K12)nagB

Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. It is acted on by 2 drugs in DrugBank.

Gene name
nagB
UniProtKB entry
P0A759Swiss-Prot
Residues / weight
266 residues · 29,774 Da
Also known as
3.5.99.6 · GlcN6P deaminase · glmD · Glucosamine-6-phosphate isomerase · GNPDA

Resolves to

Protein
UniProtP0A759UniProt nameNAGB_ECOLI
Gene
NCBI Gene945290GenBank455176
Pharmacology
KEGGecj:JW0664
Structure
PDB1CD5PDB1DEAPDB1FQO
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glucosamine-6-phosphate deaminase, and which indications are they being tested in?

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