Ras-related protein Rap-2a

BE0001843ProteinHumansRAP2A

Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form (PubMed:14966141, PubMed:15342639, PubMed:16246175, PubMed:16540189, PubMed:18930710, PubMed:20159449, PubMed:35293963). It is acted on by 2 drugs in DrugBank.

Gene name
RAP2A
UniProtKB entry
P10114Swiss-Prot
Cellular location
Midbody
Residues / weight
183 residues · 20,615 Da
Also known as
3.6.5.2 · RbBP-30

Resolves to

Protein
UniProtP10114UniProt nameRAP2A_HUMAN
Gene
HGNCHGNC:9861NCBI Gene5911GenBank35861GeneCardsRAP2A
Pharmacology
KEGGhsa:5911
Structure
PDB1KAOPDB2RAPPDB3RAP
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ras-related protein Rap-2a, and which indications are they being tested in?

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