2-amino-3-ketobutyrate coenzyme A ligase

BE0002049ProteinEscherichia coli (strain K12)kbl

Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. It is acted on by 1 drug in DrugBank.

Gene name
kbl
UniProtKB entry
P0AB77Swiss-Prot
Residues / weight
398 residues · 43,117 Da
Also known as
2.3.1.29 · AKB ligase · Glycine acetyltransferase

Resolves to

Protein
UniProtP0AB77UniProt nameKBL_ECOLI
Gene
NCBI Gene948138
Pharmacology
KEGGecj:JW3592
Structure
PDB1FC4
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
10+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on 2-amino-3-ketobutyrate coenzyme A ligase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In