Glutathione S-transferase GstA

BE0002062ProteinEscherichia coli (strain K12)gstA

Catalyzes the conjugation of reduced glutathione (GSH) to a wide number of exogenous and endogenous hydrophobic electrophiles. It is acted on by 2 drugs in DrugBank.

Gene name
gstA
UniProtKB entry
P0A9D2Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
201 residues · 22,868 Da
Also known as
2.5.1.18 · gst · GST B1-1

Resolves to

Protein
UniProtP0A9D2UniProt nameGSTA_ECOLI
Gene
NCBI Gene945758
Pharmacology
KEGGecj:JW1627
Structure
PDB1A0FPDB1N2A
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glutathione S-transferase GstA, and which indications are they being tested in?

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