Low affinity immunoglobulin gamma Fc region receptor II-a

BE0002098ProteinHumansFCGR2A

Binds to the Fc region of immunoglobulins gamma. It is acted on by 11 drugs in DrugBank.

Gene name
FCGR2A
UniProtKB entry
P12318Swiss-Prot
Cellular location
Cell membrane
Residues / weight
317 residues · 35,000 Da
Also known as
CD32 · CDw32 · Fc-gamma RII-a · Fc-gamma-RIIa · FCG2

Resolves to

Protein
UniProtP12318UniProt nameFCG2A_HUMAN
Gene
HGNCHGNC:3616NCBI Gene2212GenBank182474GeneCardsFCGR2A
Pharmacology
KEGGhsa:2212
Structure
PDB1FCGPDB1H9VPDB3D5O
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Low affinity immunoglobulin gamma Fc region receptor II-a, how selective are they, and which programs against it are still in active trials?

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