Low affinity immunoglobulin gamma Fc region receptor II-b

BE0002099ProteinHumansFCGR2B

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. It is acted on by 14 drugs in DrugBank.

Gene name
FCGR2B
UniProtKB entry
P31994Swiss-Prot
Cellular location
Cell membrane
Residues / weight
310 residues · 34,043 Da
Also known as
CD32 · CDw32 · Fc-gamma RII-b · Fc-gamma-RIIb · FCG2

Resolves to

Protein
UniProtP31994UniProt nameFCG2B_HUMAN
Gene
HGNCHGNC:3618NCBI Gene2213GenBank4099445GeneCardsFCGR2B
Pharmacology
KEGGhsa:2213
Structure
PDB2FCBPDB3WJJPDB5OCC
Drugs

What you can answer from here — as of September 07, 2019

14DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Low affinity immunoglobulin gamma Fc region receptor II-b, how selective are they, and which programs against it are still in active trials?

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