RNA-directed RNA polymerase

BE0002403ProteinHepatitis C VirusNS5b

RNA-directed RNA polymerase (Hepatitis C Virus) is a protein target in DrugBank. It is acted on by 25 drugs in DrugBank.

Gene name
NS5b
UniProtKB entry
O39930TrEMBL
Cellular location
Cytoplasmic
Residues / weight
591 residues · 65,753 Da
Also known as
2.7.7.48 · RNA-dependent RNA-polymerase

Resolves to

Protein
UniProtO39930UniProt nameO39930_9HEPC
Drugs

What you can answer from here — as of May 03, 2025

25DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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59+ReferencesStructured and connected to the statements they support
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Which approved drugs act on RNA-directed RNA polymerase, how selective are they, and which programs against it are still in active trials?

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