3-mercaptopyruvate sulfurtransferase

BE0002824ProteinEscherichia coli (strain K12)sseA

Catalyzes the transfer of sulfur from 3-mercaptopyruvate to a thiol-containing acceptor to form an intramolecular disulfide releasing hydrogen sulfide and pyruvate (Probable). It is acted on by 1 drug in DrugBank.

Gene name
sseA
UniProtKB entry
P31142Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
281 residues · 30,812 Da
Also known as
2.8.1.2 · MST · Rhodanese-like protein

Resolves to

Protein
UniProtP31142UniProt nameTHTM_ECOLI
Gene
NCBI Gene946993
Pharmacology
KEGGecj:JW2505
Structure
PDB1URH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-mercaptopyruvate sulfurtransferase, and which indications are they being tested in?

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