Bifunctional protein GlmU

BE0003075ProteinStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)glmU

Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). It is acted on by 1 drug in DrugBank.

Gene name
glmU
UniProtKB entry
Q97R46Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
459 residues · 49,344 Da
Also known as
2.7.7.23

Resolves to

Protein
UniProtQ97R46UniProt nameGLMU_STRPN
Pharmacology
KEGGspn:SP_0988
Structure
PDB1G95PDB1G97PDB1HM0
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Bifunctional protein GlmU, and which indications are they being tested in?

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