Aminodeoxychorismate lyase

BE0003132ProteinEscherichia coli (strain K12)pabC

Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. It is acted on by 1 drug in DrugBank.

Gene name
pabC
UniProtKB entry
P28305Swiss-Prot
Residues / weight
269 residues · 29,715 Da
Also known as
4-amino-4-deoxychorismate lyase · 4.1.3.38 · ADC lyase · ADCL

Resolves to

Protein
UniProtP28305UniProt namePABC_ECOLI
Gene
NCBI Gene946647
Pharmacology
KEGGecj:JW1082
Structure
PDB1ET0PDB1I2KPDB1I2L
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Aminodeoxychorismate lyase, and which indications are they being tested in?

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