Cytochrome P450 3A43

BE0003550ProteinHumansCYP3A43

Exhibits low testosterone 6-beta-hydroxylase activity in vitro. It is acted on by 15 drugs in DrugBank.

Gene name
CYP3A43
UniProtKB entry
Q9HB55Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
503 residues · 57,669 Da
Also known as
1.14.14.1

Resolves to

Protein
UniProtQ9HB55UniProt nameCP343_HUMAN
Gene
HGNCHGNC:17450NCBI Gene64816GenBank12642642GeneCardsCYP3A43
Pharmacology
KEGGhsa:64816
Drugs

What you can answer from here — as of September 07, 2019

15DrugsApproved to experimental, with action, bond type and pharmacological action
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8Metabolic reactionsDrug transformations it catalyses, substrate to product
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome P450 3A43, how selective are they, and which programs against it are still in active trials?

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