| DB00435 | Nitric Oxide | approved | yes | inducer | Details |
| DB01020 | Isosorbide mononitrate | approved | yes | activator | Details |
| DB08931 | Riociguat | approved | yes | agoniststimulator | Details |
| DB13170 | Plecanatide | approved, investigational | yes | agonist | Details |
| DB09241 | Methylene blue | approved, investigational | yes | inhibitor | Details |
| DB09282 | Molsidomine | approved, investigational | unknown | agonist | Details |
| DB09282 | Molsidomine | approved, investigational | unknown | inducer | Details |
| DB06154 | Pentaerythritol tetranitrate | approved | unknown | inducer | Details |
| DB13749 | Magnesium gluconate | approved, investigational | no | substrate | Details |