Potassium channel subfamily K member 9

BE0003583ProteinHumansKCNK9

K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. It is acted on by 7 drugs in DrugBank.

Gene name
KCNK9
UniProtKB entry
Q9NPC2Swiss-Prot
Cellular location
Cell membrane
Residues / weight
374 residues · 42,263 Da
Also known as
Acid-sensitive potassium channel protein TASK-3 · TASK3 · TWIK-related acid-sensitive K(+) channel 3 · Two pore K(+) channel KT3.2 · Two pore potassium channel KT3.2

Resolves to

Protein
UniProtQ9NPC2UniProt nameKCNK9_HUMAN
Gene
HGNCHGNC:6283NCBI Gene51305GenBank7546843GeneCardsKCNK9
Pharmacology
IUPHAR/GtoPdb520KEGGhsa:51305
Structure
PDB3P1NPDB3P1OPDB3P1P
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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36+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium channel subfamily K member 9, how selective are they, and which programs against it are still in active trials?

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