Matrilysin

BE0003690ProteinHumansMMP7

Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. It is acted on by 12 drugs in DrugBank.

Gene name
MMP7
UniProtKB entry
P09237Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
267 residues · 29,677 Da
Also known as
3.4.24.23 · Matrin · Matrix metalloproteinase-7 · MMP-7 · MPSL1

Resolves to

Protein
UniProtP09237UniProt nameMMP7_HUMAN
Gene
HGNCHGNC:7174NCBI Gene4316GenBank35799GeneCardsMMP7
Pharmacology
IUPHAR/GtoPdb1631KEGGhsa:4316
Structure
PDB1MMPPDB1MMQPDB1MMR
Drugs

What you can answer from here — as of September 07, 2019

12DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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36+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Matrilysin, how selective are they, and which programs against it are still in active trials?

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