(2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE

DB07145ExperimentalSmall molecule

(2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE: Overview.

Mechanism: Pharmacologically active on Disintegrin and metalloproteinase domain-containing protein 17
Curator reviewed
Formula / weight: C₂₅H₂₇N₃O₄ · 433.4996 g/mol (avg)

Resolves to

Compound

ChEMBLCHEMBL148169ChEBI40083PubChem6914621

Structure

InChIKeyYDMIPBHQKFOFQW-NSYGIPOTSA-NSMILES[H][C@](C)(N1CC[C@](C)(C1=O)C1=CC=C(OCC2=CC(C)=NC3=CC=CC=C23)C=C1)C(=O)NO

Targets

P78536ADAM17P45452MMP13P09237MMP7P01375TNFP22894MMP8P08254MMP3P08253MMP2P14780MMP9+2 more

What you can answer from here — as of April 02, 2025

10Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with (2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE, and which of those have an active Phase 3 trial?

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